Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up

Due to the increased prevalence of papillary thyroid carcinoma (PTC), difficult cases and unexpected events have become more common during long-term follow-up. Herein we reported four cases that exhibited poor progress during long-term follow-up. All the cases were diagnosed with PTC and treated wit...

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Main Authors: Hea Min Yu, Jae Min Lee, Kang Seo Park, Tae Sun Park, Heung Young Jin
Format: Article
Language:English
Published: Korean Endocrine Society 2013-12-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-28-335.pdf
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author Hea Min Yu
Jae Min Lee
Kang Seo Park
Tae Sun Park
Heung Young Jin
author_facet Hea Min Yu
Jae Min Lee
Kang Seo Park
Tae Sun Park
Heung Young Jin
author_sort Hea Min Yu
collection DOAJ
description Due to the increased prevalence of papillary thyroid carcinoma (PTC), difficult cases and unexpected events have become more common during long-term follow-up. Herein we reported four cases that exhibited poor progress during long-term follow-up. All the cases were diagnosed with PTC and treated with total thyroidectomy before several years, and the patients had been newly diagnosed with recurrent and metastatic PTC. These four cases included recurred PTC with invasion of large blood vessels, a concomitant second malignancy, malignant transformation, and refractoriness to treatment. Physicians should closely monitor patients to promptly address unforeseen circumstances during PTC follow-up, including PTC recurrence and metastasis. Furthermore, we suggest that the development of a management protocol for refractory or terminal PTC is also warranted.
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spelling doaj.art-1f6a3435c0bd48faa9fe63171db3afe42022-12-21T23:36:29ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782013-12-0128433534010.3803/EnM.2013.28.4.33521970Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-UpHea Min YuJae Min LeeKang Seo ParkTae Sun ParkHeung Young JinDue to the increased prevalence of papillary thyroid carcinoma (PTC), difficult cases and unexpected events have become more common during long-term follow-up. Herein we reported four cases that exhibited poor progress during long-term follow-up. All the cases were diagnosed with PTC and treated with total thyroidectomy before several years, and the patients had been newly diagnosed with recurrent and metastatic PTC. These four cases included recurred PTC with invasion of large blood vessels, a concomitant second malignancy, malignant transformation, and refractoriness to treatment. Physicians should closely monitor patients to promptly address unforeseen circumstances during PTC follow-up, including PTC recurrence and metastasis. Furthermore, we suggest that the development of a management protocol for refractory or terminal PTC is also warranted.http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-28-335.pdfThyroid cancer, papillaryLong-term follow-upRecurrence
spellingShingle Hea Min Yu
Jae Min Lee
Kang Seo Park
Tae Sun Park
Heung Young Jin
Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up
Endocrinology and Metabolism
Thyroid cancer, papillary
Long-term follow-up
Recurrence
title Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up
title_full Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up
title_fullStr Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up
title_full_unstemmed Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up
title_short Papillary Thyroid Carcinoma: Four Cases Required Caution during Long-Term Follow-Up
title_sort papillary thyroid carcinoma four cases required caution during long term follow up
topic Thyroid cancer, papillary
Long-term follow-up
Recurrence
url http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-28-335.pdf
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AT taesunpark papillarythyroidcarcinomafourcasesrequiredcautionduringlongtermfollowup
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