Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

Local actin filament formation is indispensable for development of the dendritic arbor of neurons. We show that, surprisingly, the action of single actin filament-promoting factors was insufficient for powering dendritogenesis. Instead, this required the actin nucleator Cobl and its only evolutionar...

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Bibliographic Details
Main Authors: Maryam Izadi, Eric Seemann, Dirk Schlobinski, Lukas Schwintzer, Britta Qualmann, Michael M Kessels
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
actin nucleators
functional cooperation of actin nucleators
Ca2+-steered
F-actin-supported neuronal morphogenesis
F-BAR domain protein syndapin I
dendritic branch initiation sites
Online Access:https://elifesciences.org/articles/67718

Internet

https://elifesciences.org/articles/67718

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