Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle

Objective: to analyze the inflow cannula of an implantable axial-flow blood pump for a long-term left ventricular assist system in order to minimize thromboembolic complications. Materials and methods. Hemodynamics was considered for 4 different designs of the inflow cannula, from 0 mm to 25 mm long...

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Main Authors: M. S. Nosov, G. P. Itkin, V. M. Zaiko, V. A. Malgichev
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2020-07-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/1190
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author M. S. Nosov
G. P. Itkin
V. M. Zaiko
V. A. Malgichev
author_facet M. S. Nosov
G. P. Itkin
V. M. Zaiko
V. A. Malgichev
author_sort M. S. Nosov
collection DOAJ
description Objective: to analyze the inflow cannula of an implantable axial-flow blood pump for a long-term left ventricular assist system in order to minimize thromboembolic complications. Materials and methods. Hemodynamics was considered for 4 different designs of the inflow cannula, from 0 mm to 25 mm long. Areas at the base of the cannula received the most attention. Analysis was performed using the OpenFOAM software. Results. It was revealed that sizes of stagnation and recirculation zones directly depended on the length of the cannula when placed in the left ventricle. Accordingly, longer cannula increases the risk of thrombosis. Conclusion. The design of an inflow cannula determines the likelihood of thrombosis in the cannula. Longer inflow cannula increases stagnation and recirculation zones. This provides a basis for a search for other possible modifications.
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spelling doaj.art-1f6bd2dc54914a68a5956d7c6dcd233a2023-03-13T10:37:26ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912020-07-0122210711210.15825/1995-1191-2020-2-107-112878Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricleM. S. Nosov0G. P. Itkin1V. M. Zaiko2V. A. Malgichev3Shumakov National Medical Research Center of Transplantology and Artificial Organs; Moscow Institute of Physics and TechnologyShumakov National Medical Research Center of Transplantology and Artificial Organs; Moscow Institute of Physics and TechnologyShumakov National Medical Research Center of Transplantology and Artificial Organs; Moscow Institute of Physics and TechnologyDONA-M LtdObjective: to analyze the inflow cannula of an implantable axial-flow blood pump for a long-term left ventricular assist system in order to minimize thromboembolic complications. Materials and methods. Hemodynamics was considered for 4 different designs of the inflow cannula, from 0 mm to 25 mm long. Areas at the base of the cannula received the most attention. Analysis was performed using the OpenFOAM software. Results. It was revealed that sizes of stagnation and recirculation zones directly depended on the length of the cannula when placed in the left ventricle. Accordingly, longer cannula increases the risk of thrombosis. Conclusion. The design of an inflow cannula determines the likelihood of thrombosis in the cannula. Longer inflow cannula increases stagnation and recirculation zones. This provides a basis for a search for other possible modifications.https://journal.transpl.ru/vtio/article/view/1190end-stage heart failureartificial circulatory supportleft ventricular bypassinflow cannulathromboembolic complications
spellingShingle M. S. Nosov
G. P. Itkin
V. M. Zaiko
V. A. Malgichev
Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle
Vestnik Transplantologii i Iskusstvennyh Organov
end-stage heart failure
artificial circulatory support
left ventricular bypass
inflow cannula
thromboembolic complications
title Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle
title_full Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle
title_fullStr Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle
title_full_unstemmed Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle
title_short Numerical analysis of the effect of the design of axial-flow pump cannula tip on stagnation and recirculation zones in the left ventricle
title_sort numerical analysis of the effect of the design of axial flow pump cannula tip on stagnation and recirculation zones in the left ventricle
topic end-stage heart failure
artificial circulatory support
left ventricular bypass
inflow cannula
thromboembolic complications
url https://journal.transpl.ru/vtio/article/view/1190
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