Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis.

miR-263a/b are members of a conserved family of microRNAs that are expressed in peripheral sense organs across the animal kingdom. Here we present evidence that miR-263a and miR-263b play a role in protecting Drosophila mechanosensory bristles from apoptosis by down-regulating the pro-apoptotic gene...

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Bibliographic Details
Main Authors: Valérie Hilgers, Natascha Bushati, Stephen M Cohen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2885982?pdf=render