Aerobic exercise training differentially affects ACE C- and N-domain activities in humans: Interactions with polymorphism and association with vascular reactivity

Aerobic exercise training differentially affects ACE C- and N-domain activities in humans: Interactions with polymorphism and association with vascular reactivity

Introduction: Previous studies have linked angiotensin-converting enzyme ( ACE ) insertion (I)/deletion (D) polymorphism (II, ID and DD) to physical performance. Moreover, ACE has two catalytic domains: NH2 (N) and COOH (C) with distinct functions, and their activity has been found to be modulated b...

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Bibliographic Details
Main Authors: Cléber Rene Alves, Tiago Fernandes, José Ribeiro Lemos, Flávio de Castro Magalhães, Ivani Credidio Trombetta, Guilherme Barreto Alves, Glória de Fátima Alves da Mota, Rodrigo Gonçalves Dias, Alexandre Costa Pereira, José Eduardo Krieger, Carlos Eduardo Negrão, Edilamar Menezes Oliveira
Format: Article
Language:English
Published: SAGE Publications 2018-04-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320318761725

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https://doi.org/10.1177/1470320318761725

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