Global miRNA expression reveals novel nuclear and mitochondrial interactions in Type 1 diabetes mellitus

Global miRNA expression reveals novel nuclear and mitochondrial interactions in Type 1 diabetes mellitus

BackgroundConsidering the potential role of miRNAs as biomarkers and their interaction with both nuclear and mitochondrial genes, we investigated the miRNA expression profile in type 1 diabetes (T1DM) patients, including the pathways in which they are involved considering both nuclear and mitochondr...

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Main Authors: Rafaella Sousa Ferraz, Lucas Cauê Bezerra Santos, Rebecca Lais da-Silva-Cruz, Cintia Helena Braga-da-Silva, Leandro Magalhães, Arthur Ribeiro-dos-Santos, Amanda Vidal, Tatiana Vinasco-Sandoval, Laís Reis-das-Mercês, Camille Sena-dos-Santos, Adenilson Leão Pereira, Lilian Souza D’Albuquerque Silva, Franciane T. Cunha de Melo, Ana Carolina C. Braga de Souza, Valéria S. Galvão Leal, Priscila B. Barbosa de Figueiredo, João F. Abrahão Neto, Lorena Vilhena de Moraes, Gabriela Nascimento de Lemos, Natércia Neves Marques de Queiroz, Karem Miléo Felício, Giovanna C. Cavalcante, Ândrea Ribeiro-dos-Santos, João Soares Felício
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
type 1 diabetes
miRNAs
miRnome
nuclear target
mitochondrial target
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1033809/full

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