Parameter sensitivity analysis for a stochastic model of mitochondrial apoptosis pathway.

Understanding how gene alterations induce oncogenesis plays an important role in cancer research and may be instructive for cancer prevention and treatment. We conducted a parameter sensitivity analysis to the mitochondrial apoptosis model. Both a nonlinear bifurcation analysis of the deterministic...

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Detaylı Bibliyografya
Asıl Yazarlar: Xianli Chen, Xiaoguang Li, Wei Zhao, Tiejun Li, Qi Ouyang
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2018-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0198579&type=printable