Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study
Xiucai Li,1,* Xuee Fang,2,* Ligang Zhou,1 Yanjun Mao3 1Department of Endocrinology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, People’s Republic of China; 2Department of Tuberculosis, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shangh...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2023-08-01
|
| Series: | International Journal of General Medicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/prevalence-and-factors-associated-with-depression-in-patients-with-dia-peer-reviewed-fulltext-article-IJGM |
| _version_ | 1797742650792607744 |
|---|---|
| author | Li X Fang X Zhou L Mao Y |
| author_facet | Li X Fang X Zhou L Mao Y |
| author_sort | Li X |
| collection | DOAJ |
| description | Xiucai Li,1,* Xuee Fang,2,* Ligang Zhou,1 Yanjun Mao3 1Department of Endocrinology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, People’s Republic of China; 2Department of Tuberculosis, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China; 3Department of Nursing, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ligang Zhou, Department of Endocrinology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, People’s Republic of China, Email zhouligang1n1@163.com Yanjun Mao, Department of Nursing, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China, Email maoyanjun_fk@tongji.edu.cnBackground and Objectives: A high incidence of depression has been reported in patients with pulmonary tuberculosis and diabetes mellitus (DM-PTB). However, the association between depression and DM-PTB is poorly understood and requires further investigation. This study aimed to evaluate the prevalence of depression and the associated factors in patients with DM-PTB.Methods: A cross-sectional study was conducted among DM-PTB patients at the Tuberculosis Department of Shanghai Pulmonary Hospital Affiliated to Tongji University, China, enrolled between June 2021 and October 2021. The depression status, nutritional status, and the quality of life of the patients were evaluated using Patient Health Questionnaire– 9 (PHQ-9), Nutritional Risk Screening 2002 (NRS2002), and Quality of Life Instruments for Chronic Diseases-Pulmonary Tuberculosis (QLICD-PT), respectively.Results: A total number of 280 DM-PTB patients were screened, of whom 22 were excluded for missing data. Among the 258 DM-PTB patients subjected to analysis, 199 patients (77.13%) had PHQ-9 scores above 10. The patients with depression are more likely to have a lower monthly income, body mass index (BMI), and QLICD-PT than those without depression. The NRS2002 score and glutamic pyruvic transaminase (GPT) and glutamic oxaloacetic transaminase (GOT) levels in the depression group were more likely to be higher than those in the control group. Multivariate logistic regression analysis showed that physical function [OR = 0.798, 95% confidence interval (CI), 0.716– 0.889, P < 0.001] was a protective factor against depression, whereas NRS2002 ≥ 3 (OR = 2.299, 95% CI, 1.095– 4.825, P = 0.028), GPT (OR = 1.048, 95% CI, 1.018– 1.079, P = 0.002), and social function (OR = 1.103, 95% CI, 1.033– 1.179, P = 0.004) were risk factors of depression.Conclusion: Depression in DM-PTB patients may be associated with monthly income, BMI, QLICD-PT scores, NRS2002 scores, GPT, and GOT levels.Keywords: depression, pulmonary tuberculosis, diabetes mellitus, cross-sectional study |
| first_indexed | 2024-03-12T14:43:39Z |
| format | Article |
| id | doaj.art-1f833dd2d2bb4270ab16ffdbe3807f5c |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-03-12T14:43:39Z |
| publishDate | 2023-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-1f833dd2d2bb4270ab16ffdbe3807f5c2023-08-16T02:32:29ZengDove Medical PressInternational Journal of General Medicine1178-70742023-08-01Volume 163465347285874Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional StudyLi XFang XZhou LMao YXiucai Li,1,* Xuee Fang,2,* Ligang Zhou,1 Yanjun Mao3 1Department of Endocrinology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, People’s Republic of China; 2Department of Tuberculosis, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China; 3Department of Nursing, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ligang Zhou, Department of Endocrinology, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, People’s Republic of China, Email zhouligang1n1@163.com Yanjun Mao, Department of Nursing, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, People’s Republic of China, Email maoyanjun_fk@tongji.edu.cnBackground and Objectives: A high incidence of depression has been reported in patients with pulmonary tuberculosis and diabetes mellitus (DM-PTB). However, the association between depression and DM-PTB is poorly understood and requires further investigation. This study aimed to evaluate the prevalence of depression and the associated factors in patients with DM-PTB.Methods: A cross-sectional study was conducted among DM-PTB patients at the Tuberculosis Department of Shanghai Pulmonary Hospital Affiliated to Tongji University, China, enrolled between June 2021 and October 2021. The depression status, nutritional status, and the quality of life of the patients were evaluated using Patient Health Questionnaire– 9 (PHQ-9), Nutritional Risk Screening 2002 (NRS2002), and Quality of Life Instruments for Chronic Diseases-Pulmonary Tuberculosis (QLICD-PT), respectively.Results: A total number of 280 DM-PTB patients were screened, of whom 22 were excluded for missing data. Among the 258 DM-PTB patients subjected to analysis, 199 patients (77.13%) had PHQ-9 scores above 10. The patients with depression are more likely to have a lower monthly income, body mass index (BMI), and QLICD-PT than those without depression. The NRS2002 score and glutamic pyruvic transaminase (GPT) and glutamic oxaloacetic transaminase (GOT) levels in the depression group were more likely to be higher than those in the control group. Multivariate logistic regression analysis showed that physical function [OR = 0.798, 95% confidence interval (CI), 0.716– 0.889, P < 0.001] was a protective factor against depression, whereas NRS2002 ≥ 3 (OR = 2.299, 95% CI, 1.095– 4.825, P = 0.028), GPT (OR = 1.048, 95% CI, 1.018– 1.079, P = 0.002), and social function (OR = 1.103, 95% CI, 1.033– 1.179, P = 0.004) were risk factors of depression.Conclusion: Depression in DM-PTB patients may be associated with monthly income, BMI, QLICD-PT scores, NRS2002 scores, GPT, and GOT levels.Keywords: depression, pulmonary tuberculosis, diabetes mellitus, cross-sectional studyhttps://www.dovepress.com/prevalence-and-factors-associated-with-depression-in-patients-with-dia-peer-reviewed-fulltext-article-IJGMdepressionpulmonary tuberculosisdiabetes mellituscross-sectional study |
| spellingShingle | Li X Fang X Zhou L Mao Y Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study International Journal of General Medicine depression pulmonary tuberculosis diabetes mellitus cross-sectional study |
| title | Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study |
| title_full | Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study |
| title_fullStr | Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study |
| title_full_unstemmed | Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study |
| title_short | Prevalence and Factors Associated with Depression in Patients with Diabetes Mellitus and Pulmonary Tuberculosis (DM-PTB): A Hospital-Based Cross-Sectional Study |
| title_sort | prevalence and factors associated with depression in patients with diabetes mellitus and pulmonary tuberculosis dm ptb a hospital based cross sectional study |
| topic | depression pulmonary tuberculosis diabetes mellitus cross-sectional study |
| url | https://www.dovepress.com/prevalence-and-factors-associated-with-depression-in-patients-with-dia-peer-reviewed-fulltext-article-IJGM |
| work_keys_str_mv | AT lix prevalenceandfactorsassociatedwithdepressioninpatientswithdiabetesmellitusandpulmonarytuberculosisdmptbahospitalbasedcrosssectionalstudy AT fangx prevalenceandfactorsassociatedwithdepressioninpatientswithdiabetesmellitusandpulmonarytuberculosisdmptbahospitalbasedcrosssectionalstudy AT zhoul prevalenceandfactorsassociatedwithdepressioninpatientswithdiabetesmellitusandpulmonarytuberculosisdmptbahospitalbasedcrosssectionalstudy AT maoy prevalenceandfactorsassociatedwithdepressioninpatientswithdiabetesmellitusandpulmonarytuberculosisdmptbahospitalbasedcrosssectionalstudy |