Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania
In the past decade, there has been significant progress in clinical hematology with the discovery of targeted molecules and thus the achievement of both hematologic and molecular responses. Nevertheless, chemotherapy remains the treatment of choice for many types of hematological malignancies. Aggre...
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| Format: | Article |
| Language: | English |
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Sciendo
2017-06-01
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| Series: | Romanian Journal of Internal Medicine |
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| Online Access: | https://doi.org/10.1515/rjim-2017-0006 |
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| author | Frinc Ioana Ilies Petru Zaharie Florin Dima Delia Tanase Alina Petrov Ljubomir Irimie Alexandru Berce Cristian Lisencu Cosmin Berindan-Neagoe Ioana Tomuleasa Ciprian Bojan Anca |
| author_facet | Frinc Ioana Ilies Petru Zaharie Florin Dima Delia Tanase Alina Petrov Ljubomir Irimie Alexandru Berce Cristian Lisencu Cosmin Berindan-Neagoe Ioana Tomuleasa Ciprian Bojan Anca |
| author_sort | Frinc Ioana |
| collection | DOAJ |
| description | In the past decade, there has been significant progress in clinical hematology with the discovery of targeted molecules and thus the achievement of both hematologic and molecular responses. Nevertheless, chemotherapy remains the treatment of choice for many types of hematological malignancies. Aggressive chemotherapy leads to immunosuppression, accompanied by a high rate of infections and an increased rate of treatment-related mortality. Invasive fungal infections as well as more common bacterial and viral infections are frequent in immunocompromised patients as they are difficult to diagnose and treat. Pleuropulmonary infections in immunocompromised patients are diagnosed using clinical examination, imaging and laboratory tests. Many laboratory tests are run for several days before a final result is given and are expensive. Computer tomography is a reliable technique, but it is encumbered by high irradiation and high cost, and can assess lesions larger than 1 cm. Transthoracic ultrasound is a modern method, used in the diagnostic algorithm of pleuropulmonary pathology. It allows the diagnosis of small lesions, can be performed at the patients’ bedside, with acceptable costs and no irradiation. A fast, informed and accurate medical decision is essential for a favorable outcome in immunosuppressed patients with an adjacent infection. In the current case series we present the implementation of a new protocol for the follow-up of immunocompromised patients using transthoracic ultrasonography, of great potential use in the clinic. |
| first_indexed | 2024-04-13T21:10:07Z |
| format | Article |
| id | doaj.art-1f836ec70e6b47f69f5681bfc1d2b4cb |
| institution | Directory Open Access Journal |
| issn | 2501-062X |
| language | English |
| last_indexed | 2024-04-13T21:10:07Z |
| publishDate | 2017-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Internal Medicine |
| spelling | doaj.art-1f836ec70e6b47f69f5681bfc1d2b4cb2022-12-22T02:29:51ZengSciendoRomanian Journal of Internal Medicine2501-062X2017-06-0155210311610.1515/rjim-2017-0006rjim-2017-0006Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in RomaniaFrinc Ioana0Ilies Petru1Zaharie Florin2Dima Delia3Tanase Alina4Petrov Ljubomir5Irimie Alexandru6Berce Cristian7Lisencu Cosmin8Berindan-Neagoe Ioana9Tomuleasa Ciprian10Bojan Anca11Department of Hematology, “Ion Chiricuţă” Oncology Institute, Cluj-Napoca, RomaniaDepartment of Internal Medicine, 5th Medical Clinic, Cluj-Napoca, RomaniaDepartment of Surgery, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Hematology, “Ion Chiricuţă” Oncology Institute, Cluj-Napoca, RomaniaDepartment of Stem Cell Transplantation, Fundeni Clinical Institute, Bucharest, RomaniaDepartment of Hematology, “Ion Chiricuţă” Oncology Institute, Cluj-Napoca, RomaniaDepartment of Surgery, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Surgery, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Surgery, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, RomaniaDepartment of Genetics, “Ion Chiricuţă” Oncology Institute, Cluj-Napoca, RomaniaDepartment of Hematology, “Ion Chiricuţă” Oncology Institute, Cluj-Napoca, RomaniaDepartment of Hematology, “Ion Chiricuţă” Oncology Institute, Cluj-Napoca, RomaniaIn the past decade, there has been significant progress in clinical hematology with the discovery of targeted molecules and thus the achievement of both hematologic and molecular responses. Nevertheless, chemotherapy remains the treatment of choice for many types of hematological malignancies. Aggressive chemotherapy leads to immunosuppression, accompanied by a high rate of infections and an increased rate of treatment-related mortality. Invasive fungal infections as well as more common bacterial and viral infections are frequent in immunocompromised patients as they are difficult to diagnose and treat. Pleuropulmonary infections in immunocompromised patients are diagnosed using clinical examination, imaging and laboratory tests. Many laboratory tests are run for several days before a final result is given and are expensive. Computer tomography is a reliable technique, but it is encumbered by high irradiation and high cost, and can assess lesions larger than 1 cm. Transthoracic ultrasound is a modern method, used in the diagnostic algorithm of pleuropulmonary pathology. It allows the diagnosis of small lesions, can be performed at the patients’ bedside, with acceptable costs and no irradiation. A fast, informed and accurate medical decision is essential for a favorable outcome in immunosuppressed patients with an adjacent infection. In the current case series we present the implementation of a new protocol for the follow-up of immunocompromised patients using transthoracic ultrasonography, of great potential use in the clinic.https://doi.org/10.1515/rjim-2017-0006hematological malignanciesimmunosuppressiontransthoracic ultrasoundantibioticsantifungal treatment |
| spellingShingle | Frinc Ioana Ilies Petru Zaharie Florin Dima Delia Tanase Alina Petrov Ljubomir Irimie Alexandru Berce Cristian Lisencu Cosmin Berindan-Neagoe Ioana Tomuleasa Ciprian Bojan Anca Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania Romanian Journal of Internal Medicine hematological malignancies immunosuppression transthoracic ultrasound antibiotics antifungal treatment |
| title | Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania |
| title_full | Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania |
| title_fullStr | Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania |
| title_full_unstemmed | Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania |
| title_short | Transthoracic ultrasonography for the immunocompromised patient. A pilot project that introduces transthoracic ultrasonography for the follow-up of hematological patients in Romania |
| title_sort | transthoracic ultrasonography for the immunocompromised patient a pilot project that introduces transthoracic ultrasonography for the follow up of hematological patients in romania |
| topic | hematological malignancies immunosuppression transthoracic ultrasound antibiotics antifungal treatment |
| url | https://doi.org/10.1515/rjim-2017-0006 |
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