The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19
Background Clinical and radiographic outcomes after mechanical thrombectomy in the setting of COVID‐19 infection remain poorly characterized. We sought to determine how COVID‐19 status affects mechanical thrombectomy outcomes in the real‐world setting in the United States. Methods The prospectively...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-07-01
|
| Series: | Stroke: Vascular and Interventional Neurology |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/SVIN.122.000329 |
| _version_ | 1797371962502152192 |
|---|---|
| author | Ameer E. Hassan Wondwossen G. Tekle Sohum K. Desai Diogo C. Haussen Mahmoud Mohammaden Raul G. Nogueira Sunil A., Sheth Sergio Salazar‐Marioni Alexandra Czap Italo Linfante Guilherme Dabus Amy K. Starosciak Thanh N. Nguyen Mohamad Abdalkader Piers Klein James E. Siegler Mark Heslin Lauren Thau Solomon Oak Santiago Ortega‐Gutierrez Mudassir Farooqui Juan Vivanco‐Suarez Shahram Majidi Johanna T. Fifi Stavros Matsoukas Weston Gordon Guillermo Linares Wilson Rodriguez Brijesh P. Mehta Rebecca Sugg Mohammed Jumaa David S. Liebeskind |
| author_facet | Ameer E. Hassan Wondwossen G. Tekle Sohum K. Desai Diogo C. Haussen Mahmoud Mohammaden Raul G. Nogueira Sunil A., Sheth Sergio Salazar‐Marioni Alexandra Czap Italo Linfante Guilherme Dabus Amy K. Starosciak Thanh N. Nguyen Mohamad Abdalkader Piers Klein James E. Siegler Mark Heslin Lauren Thau Solomon Oak Santiago Ortega‐Gutierrez Mudassir Farooqui Juan Vivanco‐Suarez Shahram Majidi Johanna T. Fifi Stavros Matsoukas Weston Gordon Guillermo Linares Wilson Rodriguez Brijesh P. Mehta Rebecca Sugg Mohammed Jumaa David S. Liebeskind |
| author_sort | Ameer E. Hassan |
| collection | DOAJ |
| description | Background Clinical and radiographic outcomes after mechanical thrombectomy in the setting of COVID‐19 infection remain poorly characterized. We sought to determine how COVID‐19 status affects mechanical thrombectomy outcomes in the real‐world setting in the United States. Methods The prospectively maintained multicenter mechanical thrombectomy registry from the Society of Vascular and Interventional Neurology was queried for baseline clinical characteristics among patients with and without COVID‐19 who underwent mechanical thrombectomy between March 1 and December 31, 2020 at 12 sites. Primary outcome was the likelihood of good neurological outcomes (90 day modified Rankin scale 0–2) among patients with COVID‐19 treated with endovascular thrombectomy, which was assessed using multivariable logistic regression adjusted for age, National Institutes of Health Stroke Scale, Alberta Stroke Program Early CT Score, and substantial reperfusion (modified Thrombolysis in Cerebral Infarction 2b, 2c, and 3). Secondary outcomes included National Institutes of Health Stroke Scale at 24 hours. Results Among 915 patients who underwent mechanical thrombectomy during the study period, 51 patients were positive for COVID‐19 (5.6%). Univariate analysis revealed that compared with patients who were COVID‐19 negative, patients who were positive for COVID‐19 were more likely to be male, nonsmokers, have lower Alberta Stroke Program Early CT Score, and present with intracranial internal carotid artery occlusions (Table 1). They were also less likely to achieve successful reperfusion. Multivariable analysis, however, failed to identify any independent associations with COVID‐19 positive status. Conclusion In our cohort, patients postive for COVID‐19 with acute ischemic stroke who undergo mechanical thrombectomy have similar baseline characteristics, imaging features, procedural, and clinical outcomes compared to patients who are negative for COVID‐19 in multivariate analysis. Further analyses are warranted. |
| first_indexed | 2024-03-08T18:28:24Z |
| format | Article |
| id | doaj.art-1f89729227cd45f5814de859505be238 |
| institution | Directory Open Access Journal |
| issn | 2694-5746 |
| language | English |
| last_indexed | 2024-03-08T18:28:24Z |
| publishDate | 2023-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Stroke: Vascular and Interventional Neurology |
| spelling | doaj.art-1f89729227cd45f5814de859505be2382023-12-30T07:09:27ZengWileyStroke: Vascular and Interventional Neurology2694-57462023-07-013410.1161/SVIN.122.000329The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19Ameer E. Hassan0Wondwossen G. Tekle1Sohum K. Desai2Diogo C. Haussen3Mahmoud Mohammaden4Raul G. Nogueira5Sunil A., Sheth6Sergio Salazar‐Marioni7Alexandra Czap8Italo Linfante9Guilherme Dabus10Amy K. Starosciak11Thanh N. Nguyen12Mohamad Abdalkader13Piers Klein14James E. Siegler15Mark Heslin16Lauren Thau17Solomon Oak18Santiago Ortega‐Gutierrez19Mudassir Farooqui20Juan Vivanco‐Suarez21Shahram Majidi22Johanna T. Fifi23Stavros Matsoukas24Weston Gordon25Guillermo Linares26Wilson Rodriguez27Brijesh P. Mehta28Rebecca Sugg29Mohammed Jumaa30David S. Liebeskind31Valley Baptist Medical Center and University of Texas Rio Grande Valley School of Medicine Harlingen TXValley Baptist Medical Center and University of Texas Rio Grande Valley School of Medicine Harlingen TXValley Baptist Medical Center and University of Texas Rio Grande Valley School of Medicine Harlingen TXEmory University Atlanta GAEmory University Atlanta GAEmory University Atlanta GAUniversity of Texas Health Science Center Houston TXUniversity of Texas Health Science Center Houston TXUniversity of Texas Health Science Center Houston TXMiami Cardiac & Vascular Institute and Miami Neuroscience Institute Baptist Health South Florida Miami FLMiami Cardiac & Vascular Institute and Miami Neuroscience Institute Baptist Health South Florida Miami FLMiami Cardiac & Vascular Institute and Miami Neuroscience Institute Baptist Health South Florida Miami FLBoston Medical Center Boston MABoston Medical Center Boston MABoston Medical Center Boston MACooper Neurological Institute Cooper University Hospital Camden NJCooper Neurological Institute Cooper University Hospital Camden NJCooper Neurological Institute Cooper University Hospital Camden NJCooper Neurological Institute Cooper University Hospital Camden NJUniversity of Iowa Hospitals and Clinics IAUniversity of Iowa Hospitals and Clinics IAUniversity of Iowa Hospitals and Clinics IAMt Sinai NYMt Sinai NYMt Sinai NYSaint Louis University MOSaint Louis University MOSaint Louis University MOMemorial Neuroscience Institute Pembroke Pines FLUniversity of South Alabama Mobile ALUniversity of Toledo Toledo OHUniversity of California Los Angeles Los Angeles CABackground Clinical and radiographic outcomes after mechanical thrombectomy in the setting of COVID‐19 infection remain poorly characterized. We sought to determine how COVID‐19 status affects mechanical thrombectomy outcomes in the real‐world setting in the United States. Methods The prospectively maintained multicenter mechanical thrombectomy registry from the Society of Vascular and Interventional Neurology was queried for baseline clinical characteristics among patients with and without COVID‐19 who underwent mechanical thrombectomy between March 1 and December 31, 2020 at 12 sites. Primary outcome was the likelihood of good neurological outcomes (90 day modified Rankin scale 0–2) among patients with COVID‐19 treated with endovascular thrombectomy, which was assessed using multivariable logistic regression adjusted for age, National Institutes of Health Stroke Scale, Alberta Stroke Program Early CT Score, and substantial reperfusion (modified Thrombolysis in Cerebral Infarction 2b, 2c, and 3). Secondary outcomes included National Institutes of Health Stroke Scale at 24 hours. Results Among 915 patients who underwent mechanical thrombectomy during the study period, 51 patients were positive for COVID‐19 (5.6%). Univariate analysis revealed that compared with patients who were COVID‐19 negative, patients who were positive for COVID‐19 were more likely to be male, nonsmokers, have lower Alberta Stroke Program Early CT Score, and present with intracranial internal carotid artery occlusions (Table 1). They were also less likely to achieve successful reperfusion. Multivariable analysis, however, failed to identify any independent associations with COVID‐19 positive status. Conclusion In our cohort, patients postive for COVID‐19 with acute ischemic stroke who undergo mechanical thrombectomy have similar baseline characteristics, imaging features, procedural, and clinical outcomes compared to patients who are negative for COVID‐19 in multivariate analysis. Further analyses are warranted.https://www.ahajournals.org/doi/10.1161/SVIN.122.000329acute strokeCOVID‐19mechanical thrombectomy |
| spellingShingle | Ameer E. Hassan Wondwossen G. Tekle Sohum K. Desai Diogo C. Haussen Mahmoud Mohammaden Raul G. Nogueira Sunil A., Sheth Sergio Salazar‐Marioni Alexandra Czap Italo Linfante Guilherme Dabus Amy K. Starosciak Thanh N. Nguyen Mohamad Abdalkader Piers Klein James E. Siegler Mark Heslin Lauren Thau Solomon Oak Santiago Ortega‐Gutierrez Mudassir Farooqui Juan Vivanco‐Suarez Shahram Majidi Johanna T. Fifi Stavros Matsoukas Weston Gordon Guillermo Linares Wilson Rodriguez Brijesh P. Mehta Rebecca Sugg Mohammed Jumaa David S. Liebeskind The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19 Stroke: Vascular and Interventional Neurology acute stroke COVID‐19 mechanical thrombectomy |
| title | The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19 |
| title_full | The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19 |
| title_fullStr | The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19 |
| title_full_unstemmed | The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19 |
| title_short | The Society of Vascular and Interventional Neurology (SVIN) Mechanical Thrombectomy Registry: Outcomes in Patients With Acute Ischemic Stroke and COVID‐19 |
| title_sort | society of vascular and interventional neurology svin mechanical thrombectomy registry outcomes in patients with acute ischemic stroke and covid 19 |
| topic | acute stroke COVID‐19 mechanical thrombectomy |
| url | https://www.ahajournals.org/doi/10.1161/SVIN.122.000329 |
| work_keys_str_mv | AT ameerehassan thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT wondwossengtekle thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT sohumkdesai thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT diogochaussen thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mahmoudmohammaden thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT raulgnogueira thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT sunilasheth thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT sergiosalazarmarioni thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT alexandraczap thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT italolinfante thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT guilhermedabus thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT amykstarosciak thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT thanhnnguyen thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mohamadabdalkader thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT piersklein thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT jamesesiegler thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT markheslin thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT laurenthau thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT solomonoak thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT santiagoortegagutierrez thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mudassirfarooqui thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT juanvivancosuarez thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT shahrammajidi thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT johannatfifi thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT stavrosmatsoukas thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT westongordon thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT guillermolinares thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT wilsonrodriguez thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT brijeshpmehta thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT rebeccasugg thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mohammedjumaa thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT davidsliebeskind thesocietyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT ameerehassan societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT wondwossengtekle societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT sohumkdesai societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT diogochaussen societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mahmoudmohammaden societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT raulgnogueira societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT sunilasheth societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT sergiosalazarmarioni societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT alexandraczap societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT italolinfante societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT guilhermedabus societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT amykstarosciak societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT thanhnnguyen societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mohamadabdalkader societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT piersklein societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT jamesesiegler societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT markheslin societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT laurenthau societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT solomonoak societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT santiagoortegagutierrez societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mudassirfarooqui societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT juanvivancosuarez societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT shahrammajidi societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT johannatfifi societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT stavrosmatsoukas societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT westongordon societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT guillermolinares societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT wilsonrodriguez societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT brijeshpmehta societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT rebeccasugg societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT mohammedjumaa societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 AT davidsliebeskind societyofvascularandinterventionalneurologysvinmechanicalthrombectomyregistryoutcomesinpatientswithacuteischemicstrokeandcovid19 |