A Case with Improvement of Blepharospasm by Zolpidem

Zolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral spasms of the eyelids for 20 years. She has been treated with botu...

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Main Authors: Munkyung Sunwoo, Junghee Cho, Jun Hong Lee, Gyu Sik Kim, Jong Hun Kim, Sun-Ah Choi
Format: Article
Language:English
Published: Korean Movement Disorder Society 2011-05-01
Series:Journal of Movement Disorders
Subjects:
Online Access:http://e-jmd.org/upload/jmd-4-1-53-10.pdf
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author Munkyung Sunwoo
Junghee Cho
Jun Hong Lee
Gyu Sik Kim
Jong Hun Kim
Sun-Ah Choi
author_facet Munkyung Sunwoo
Junghee Cho
Jun Hong Lee
Gyu Sik Kim
Jong Hun Kim
Sun-Ah Choi
author_sort Munkyung Sunwoo
collection DOAJ
description Zolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral spasms of the eyelids for 20 years. She has been treated with botulinum toxin injection and taken some medications. But, she experienced a little effect and was not satisfied with those treatments. Her symptom was improved after taking Zolpidem which had been prescribed for insomnia by her primary physician. She did not show any improvement after placebo injection and neostigmine test. This is the first report which shows improvement of isolated blepharospasm by Zolpidem in Korea. Zolpidem can be one of useful alternative pharmacological treatments for blepharospasm. Further randomized, blinded, placebo-controlled studies are needed to validate this finding.
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spelling doaj.art-1f8b107ccb314acc869f02e3adef1fdd2023-09-02T18:53:33ZengKorean Movement Disorder SocietyJournal of Movement Disorders2005-940X2093-49392011-05-0141535410.14802/jmd.1101041A Case with Improvement of Blepharospasm by ZolpidemMunkyung SunwooJunghee ChoJun Hong LeeGyu Sik KimJong Hun KimSun-Ah ChoiZolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral spasms of the eyelids for 20 years. She has been treated with botulinum toxin injection and taken some medications. But, she experienced a little effect and was not satisfied with those treatments. Her symptom was improved after taking Zolpidem which had been prescribed for insomnia by her primary physician. She did not show any improvement after placebo injection and neostigmine test. This is the first report which shows improvement of isolated blepharospasm by Zolpidem in Korea. Zolpidem can be one of useful alternative pharmacological treatments for blepharospasm. Further randomized, blinded, placebo-controlled studies are needed to validate this finding.http://e-jmd.org/upload/jmd-4-1-53-10.pdfZolpidemBlepharospasmDystonia
spellingShingle Munkyung Sunwoo
Junghee Cho
Jun Hong Lee
Gyu Sik Kim
Jong Hun Kim
Sun-Ah Choi
A Case with Improvement of Blepharospasm by Zolpidem
Journal of Movement Disorders
Zolpidem
Blepharospasm
Dystonia
title A Case with Improvement of Blepharospasm by Zolpidem
title_full A Case with Improvement of Blepharospasm by Zolpidem
title_fullStr A Case with Improvement of Blepharospasm by Zolpidem
title_full_unstemmed A Case with Improvement of Blepharospasm by Zolpidem
title_short A Case with Improvement of Blepharospasm by Zolpidem
title_sort case with improvement of blepharospasm by zolpidem
topic Zolpidem
Blepharospasm
Dystonia
url http://e-jmd.org/upload/jmd-4-1-53-10.pdf
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