A Case with Improvement of Blepharospasm by Zolpidem
Zolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral spasms of the eyelids for 20 years. She has been treated with botu...
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Format: | Article |
Language: | English |
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Korean Movement Disorder Society
2011-05-01
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Series: | Journal of Movement Disorders |
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Online Access: | http://e-jmd.org/upload/jmd-4-1-53-10.pdf |
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author | Munkyung Sunwoo Junghee Cho Jun Hong Lee Gyu Sik Kim Jong Hun Kim Sun-Ah Choi |
author_facet | Munkyung Sunwoo Junghee Cho Jun Hong Lee Gyu Sik Kim Jong Hun Kim Sun-Ah Choi |
author_sort | Munkyung Sunwoo |
collection | DOAJ |
description | Zolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral spasms of the eyelids for 20 years. She has been treated with botulinum toxin injection and taken some medications. But, she experienced a little effect and was not satisfied with those treatments. Her symptom was improved after taking Zolpidem which had been prescribed for insomnia by her primary physician. She did not show any improvement after placebo injection and neostigmine test. This is the first report which shows improvement of isolated blepharospasm by Zolpidem in Korea. Zolpidem can be one of useful alternative pharmacological treatments for blepharospasm. Further randomized, blinded, placebo-controlled studies are needed to validate this finding. |
first_indexed | 2024-03-12T08:15:33Z |
format | Article |
id | doaj.art-1f8b107ccb314acc869f02e3adef1fdd |
institution | Directory Open Access Journal |
issn | 2005-940X 2093-4939 |
language | English |
last_indexed | 2024-03-12T08:15:33Z |
publishDate | 2011-05-01 |
publisher | Korean Movement Disorder Society |
record_format | Article |
series | Journal of Movement Disorders |
spelling | doaj.art-1f8b107ccb314acc869f02e3adef1fdd2023-09-02T18:53:33ZengKorean Movement Disorder SocietyJournal of Movement Disorders2005-940X2093-49392011-05-0141535410.14802/jmd.1101041A Case with Improvement of Blepharospasm by ZolpidemMunkyung SunwooJunghee ChoJun Hong LeeGyu Sik KimJong Hun KimSun-Ah ChoiZolpidem is usually used for the treatment of insomnia as a hypnotic drug. It was also suggested to be effective in the treatment of dystonia in some studies. A 74-year-old woman had been suffering from frequent and intense bilateral spasms of the eyelids for 20 years. She has been treated with botulinum toxin injection and taken some medications. But, she experienced a little effect and was not satisfied with those treatments. Her symptom was improved after taking Zolpidem which had been prescribed for insomnia by her primary physician. She did not show any improvement after placebo injection and neostigmine test. This is the first report which shows improvement of isolated blepharospasm by Zolpidem in Korea. Zolpidem can be one of useful alternative pharmacological treatments for blepharospasm. Further randomized, blinded, placebo-controlled studies are needed to validate this finding.http://e-jmd.org/upload/jmd-4-1-53-10.pdfZolpidemBlepharospasmDystonia |
spellingShingle | Munkyung Sunwoo Junghee Cho Jun Hong Lee Gyu Sik Kim Jong Hun Kim Sun-Ah Choi A Case with Improvement of Blepharospasm by Zolpidem Journal of Movement Disorders Zolpidem Blepharospasm Dystonia |
title | A Case with Improvement of Blepharospasm by Zolpidem |
title_full | A Case with Improvement of Blepharospasm by Zolpidem |
title_fullStr | A Case with Improvement of Blepharospasm by Zolpidem |
title_full_unstemmed | A Case with Improvement of Blepharospasm by Zolpidem |
title_short | A Case with Improvement of Blepharospasm by Zolpidem |
title_sort | case with improvement of blepharospasm by zolpidem |
topic | Zolpidem Blepharospasm Dystonia |
url | http://e-jmd.org/upload/jmd-4-1-53-10.pdf |
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