The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis
BACKGROUND: Dental status and oral hygiene are associated with progression of atherosclerosis in patients with carotid stenosis. It remains unclear whether dental disease is a risk factor for mortality in these patients.We evaluated the bearing of dental disease on mortality among patients with...
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2011-07-01
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| Series: | Swiss Medical Weekly |
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| Online Access: | https://www.smw.ch/index.php/smw/article/view/1322 |
| _version_ | 1811288968889630720 |
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| author | M Hoke T Schillinger W Mlekusch O Wagner E Minar M Schillinger |
| author_facet | M Hoke T Schillinger W Mlekusch O Wagner E Minar M Schillinger |
| author_sort | M Hoke |
| collection | DOAJ |
| description |
BACKGROUND: Dental status and oral hygiene are associated with progression of atherosclerosis in patients with carotid stenosis. It remains unclear whether dental disease is a risk factor for mortality in these patients.We evaluated the bearing of dental disease on mortality among patients with asymptomatic carotid atherosclerosis.
METHODS: Three World Health Organization-validatedindices in 411 patients with asymptomatic carotid atherosclerosis were evaluated, measuring DMFT (decayed, missing, filled teeth) for dental status, CPITN (community periodontal index for treatmentneeds) for periodontal statusand SLI (Silness-LöeIndex) for oral hygiene respectively. Patients were prospectively followed for median 6.2 years (IQR 5.8 to 6.6 years) for all-cause mortality.
RESULTS: During follow-up, 107 (26%) deaths occurred (74 cardiovascular causes). DMFT and SLI, but not CPITN, showed a significant and gradual association with mortality. For continuous variables, the adjusted hazard ratios (HR) for death were 1.06 (95% CI 1.0 to 1.12; p = 0.04) for DMFT, and 1.43 (95% CI, 1.01 to 2.03; p = 0.04) for SLI respectively. Edentulousness was a significant risk factor for death (adjusted HR 1.99, 95%CI, 1.18 to 3.02; p = 0.008).
CONCLUSION: Dental status and oral hygiene were associated with mortality in patients with carotid atherosclerosis regardless of conventional cardiovascular risk factors.
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| first_indexed | 2024-04-13T03:45:27Z |
| format | Article |
| id | doaj.art-1f8ca54b78a14b03a8cab9680f6616ad |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-13T03:45:27Z |
| publishDate | 2011-07-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-1f8ca54b78a14b03a8cab9680f6616ad2022-12-22T03:04:01ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972011-07-01141293010.4414/smw.2011.13236The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosisM HokeT SchillingerW MlekuschO WagnerE MinarM Schillinger BACKGROUND: Dental status and oral hygiene are associated with progression of atherosclerosis in patients with carotid stenosis. It remains unclear whether dental disease is a risk factor for mortality in these patients.We evaluated the bearing of dental disease on mortality among patients with asymptomatic carotid atherosclerosis. METHODS: Three World Health Organization-validatedindices in 411 patients with asymptomatic carotid atherosclerosis were evaluated, measuring DMFT (decayed, missing, filled teeth) for dental status, CPITN (community periodontal index for treatmentneeds) for periodontal statusand SLI (Silness-LöeIndex) for oral hygiene respectively. Patients were prospectively followed for median 6.2 years (IQR 5.8 to 6.6 years) for all-cause mortality. RESULTS: During follow-up, 107 (26%) deaths occurred (74 cardiovascular causes). DMFT and SLI, but not CPITN, showed a significant and gradual association with mortality. For continuous variables, the adjusted hazard ratios (HR) for death were 1.06 (95% CI 1.0 to 1.12; p = 0.04) for DMFT, and 1.43 (95% CI, 1.01 to 2.03; p = 0.04) for SLI respectively. Edentulousness was a significant risk factor for death (adjusted HR 1.99, 95%CI, 1.18 to 3.02; p = 0.008). CONCLUSION: Dental status and oral hygiene were associated with mortality in patients with carotid atherosclerosis regardless of conventional cardiovascular risk factors. https://www.smw.ch/index.php/smw/article/view/1322carotid atherosclerosisdental diseasemortalityoral hygienescreening |
| spellingShingle | M Hoke T Schillinger W Mlekusch O Wagner E Minar M Schillinger The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis Swiss Medical Weekly carotid atherosclerosis dental disease mortality oral hygiene screening |
| title | The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis |
| title_full | The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis |
| title_fullStr | The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis |
| title_full_unstemmed | The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis |
| title_short | The impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis |
| title_sort | impact of dental disease on mortality in patients with asymptomatic carotid atherosclerosis |
| topic | carotid atherosclerosis dental disease mortality oral hygiene screening |
| url | https://www.smw.ch/index.php/smw/article/view/1322 |
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