Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells

Widespread uncoupling between transcriptome and translatome variations after a stimulus in mammalian cells

<p>Abstract</p> <p>Background</p> <p>The classical view on eukaryotic gene expression proposes the scheme of a forward flow for which fluctuations in mRNA levels upon a stimulus contribute to determine variations in mRNA availability for translation. Here we address thi...

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Bibliographic Details
Main Authors: Tebaldi Toma, Re Angela, Viero Gabriella, Pegoretti Ilaria, Passerini Andrea, Blanzieri Enrico, Quattrone Alessandro
Format: Article
Language:English
Published: BMC 2012-06-01
Series:BMC Genomics
Subjects:
Polysomal
Profiling
Transcriptome
Translational
Control
Translatome
Online Access:http://www.biomedcentral.com/1471-2164/13/220

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