Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil
Abstract: INTRODUCTION: Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic charac...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Medicina Tropical (SBMT)
2016-02-01
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| Series: | Revista da Sociedade Brasileira de Medicina Tropical |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100024&lng=en&tlng=en |
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| author | Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho |
| author_facet | Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho |
| author_sort | Luiz Euribel Prestes-Carneiro |
| collection | DOAJ |
| description | Abstract: INTRODUCTION: Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic characteristics of patients diagnosed with HBV who were followed up at an infectious diseases clinic of a public hospital in State of São Paulo, Brazil. METHODS: Medical records of patients aged >18 years and diagnosed with HBV infection between January 2000 and December 2013 were reviewed. RESULTS: Seventy-five patients were enrolled with male-female main infection-associated risk factors; 9 (12%) were co-infected with human immunodeficiency virus (HIV), 5 (6.7%) with hepatitis C virus (HCV), and 3 (4%) were co-infected with both HIV and HCV. Antiviral HBV therapy was applied in 21 (28%) patients and tenofovir monotherapy was the most prescribed medication. After approximately 2 years of antiviral treatment, the HBV-DNA viral load was undetectable in 12 (92.3%) patients and lower levels of alanine aminotransferase were found in these patients. CONCLUSIONS: Over a 13-year interval, very few individuals infected with HBV were identified, highlighting the barriers for caring for patients with HBV in developing countries. New measures need to be implemented to complement curative practices. |
| first_indexed | 2024-12-12T11:28:24Z |
| format | Article |
| id | doaj.art-1f942bcd7f6f474f97f2679d88f7b93b |
| institution | Directory Open Access Journal |
| issn | 1678-9849 |
| language | English |
| last_indexed | 2024-12-12T11:28:24Z |
| publishDate | 2016-02-01 |
| publisher | Sociedade Brasileira de Medicina Tropical (SBMT) |
| record_format | Article |
| series | Revista da Sociedade Brasileira de Medicina Tropical |
| spelling | doaj.art-1f942bcd7f6f474f97f2679d88f7b93b2022-12-22T00:25:52ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical1678-98492016-02-01491242810.1590/0037-8682-0315-2015S0037-86822016000100024Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, BrazilLuiz Euribel Prestes-CarneiroJessyka Thaiza Menezes VieiraLuiza Bellintani IsaacAlexandre Martins Portelinha FilhoAbstract: INTRODUCTION: Few studies have addressed the primary characteristics of patients infected with hepatitis B virus (HBV) in the general population, especially those living in small- and medium-sized cities in Brazil. We aimed to determine the clinical, demographic, and epidemiologic characteristics of patients diagnosed with HBV who were followed up at an infectious diseases clinic of a public hospital in State of São Paulo, Brazil. METHODS: Medical records of patients aged >18 years and diagnosed with HBV infection between January 2000 and December 2013 were reviewed. RESULTS: Seventy-five patients were enrolled with male-female main infection-associated risk factors; 9 (12%) were co-infected with human immunodeficiency virus (HIV), 5 (6.7%) with hepatitis C virus (HCV), and 3 (4%) were co-infected with both HIV and HCV. Antiviral HBV therapy was applied in 21 (28%) patients and tenofovir monotherapy was the most prescribed medication. After approximately 2 years of antiviral treatment, the HBV-DNA viral load was undetectable in 12 (92.3%) patients and lower levels of alanine aminotransferase were found in these patients. CONCLUSIONS: Over a 13-year interval, very few individuals infected with HBV were identified, highlighting the barriers for caring for patients with HBV in developing countries. New measures need to be implemented to complement curative practices.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100024&lng=en&tlng=enHepatitis B vírusEpidemiologyRisk factorsAntiviral treatment |
| spellingShingle | Luiz Euribel Prestes-Carneiro Jessyka Thaiza Menezes Vieira Luiza Bellintani Isaac Alexandre Martins Portelinha Filho Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil Revista da Sociedade Brasileira de Medicina Tropical Hepatitis B vírus Epidemiology Risk factors Antiviral treatment |
| title | Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
| title_full | Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
| title_fullStr | Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
| title_full_unstemmed | Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
| title_short | Clinical, demographic, and epidemiologic characteristics of hepatitis B virus-infected patients at a tertiary public hospital in Presidente Prudente, State of São Paulo, Brazil |
| title_sort | clinical demographic and epidemiologic characteristics of hepatitis b virus infected patients at a tertiary public hospital in presidente prudente state of sao paulo brazil |
| topic | Hepatitis B vírus Epidemiology Risk factors Antiviral treatment |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000100024&lng=en&tlng=en |
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