Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children
Purpose: Periocular molluscum contagiosum can cause a chronic secondary follicular conjunctivitis or keratoconjunctivitis that rarely leads to corneal scarring and visual impairment. We describe two cases of follicular conjunctivitis due to periocular molluscum contagiosum that were successfully tre...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-03-01
|
| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993622000810 |
| _version_ | 1819283871558008832 |
|---|---|
| author | Jonathan S. Yi Kellie R. Satterfield Catherine S. Choi Markus D. Boos Michelle T. Cabrera |
| author_facet | Jonathan S. Yi Kellie R. Satterfield Catherine S. Choi Markus D. Boos Michelle T. Cabrera |
| author_sort | Jonathan S. Yi |
| collection | DOAJ |
| description | Purpose: Periocular molluscum contagiosum can cause a chronic secondary follicular conjunctivitis or keratoconjunctivitis that rarely leads to corneal scarring and visual impairment. We describe two cases of follicular conjunctivitis due to periocular molluscum contagiosum that were successfully treated with topical adapalene 0.1%. Observations: Case 1 is a 9-year old female with a history of leg molluscum contagiosum who presented with three 1mm flesh-colored umbilicated papules on the periocular skin of the right eye with associated follicular conjunctivitis and diffuse corneal punctate epithelial erosions. Ocular symptoms were persistent for 6 months. Case 2 is a 4-year old female with a 3-month history of right periocular bumps and one month of conjunctival redness with eyelid edema. Examination revealed umbilicated flesh colored nodules on the right upper and lower eyelids with associated trace conjunctival injection. Both patients experienced rapid resolution of both eyelid involvement and conjunctivitis following the use of twice daily topical adapalene 0.1% to the eyelid lesions, with no reported side effects. Conclusions and importance: Topical adapalene 0.1% is a cost-effective, convenient, and non-toxic over-the-counter retinoid cream that should be considered for first-line therapy in the treatment of periocular molluscum contagiosum and any associated conjunctivitis. |
| first_indexed | 2024-12-24T01:38:22Z |
| format | Article |
| id | doaj.art-1f990ae0515440e491445f42de8f5746 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-24T01:38:22Z |
| publishDate | 2022-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-1f990ae0515440e491445f42de8f57462022-12-21T17:22:07ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-03-0125101335Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in childrenJonathan S. Yi0Kellie R. Satterfield1Catherine S. Choi2Markus D. Boos3Michelle T. Cabrera4Department of Ophthalmology, University of Washington, Seattle, WA, USADepartment of Ophthalmology, University of Washington, Seattle, WA, USANewton Wellesley Eye Associates in Newton, Massachusetts, USA; Department of Ophthalmology, New England Eye Center, Tufts Medical Center, Boston, MA, USADivision of Dermatology, Department of Pediatrics, University of Washington School of Medicine and Seattle Children's Hospital, Seattle, WA, USADepartment of Ophthalmology, University of Washington, Seattle, WA, USA; Department of Ophthalmology, Seattle Children's Hospital, Seattle, WA, USA; Corresponding author. Department of Ophthalmology Seattle Children's Hospital, 4800 Sand point Way, OA.9.220, Seattle, WA 98105, USA.Purpose: Periocular molluscum contagiosum can cause a chronic secondary follicular conjunctivitis or keratoconjunctivitis that rarely leads to corneal scarring and visual impairment. We describe two cases of follicular conjunctivitis due to periocular molluscum contagiosum that were successfully treated with topical adapalene 0.1%. Observations: Case 1 is a 9-year old female with a history of leg molluscum contagiosum who presented with three 1mm flesh-colored umbilicated papules on the periocular skin of the right eye with associated follicular conjunctivitis and diffuse corneal punctate epithelial erosions. Ocular symptoms were persistent for 6 months. Case 2 is a 4-year old female with a 3-month history of right periocular bumps and one month of conjunctival redness with eyelid edema. Examination revealed umbilicated flesh colored nodules on the right upper and lower eyelids with associated trace conjunctival injection. Both patients experienced rapid resolution of both eyelid involvement and conjunctivitis following the use of twice daily topical adapalene 0.1% to the eyelid lesions, with no reported side effects. Conclusions and importance: Topical adapalene 0.1% is a cost-effective, convenient, and non-toxic over-the-counter retinoid cream that should be considered for first-line therapy in the treatment of periocular molluscum contagiosum and any associated conjunctivitis.http://www.sciencedirect.com/science/article/pii/S2451993622000810Periocular molluscum contagiosumMolluscum contagiosumConjunctivitisKeratoconjunctivitisTopical adapaleneRetinoid |
| spellingShingle | Jonathan S. Yi Kellie R. Satterfield Catherine S. Choi Markus D. Boos Michelle T. Cabrera Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children American Journal of Ophthalmology Case Reports Periocular molluscum contagiosum Molluscum contagiosum Conjunctivitis Keratoconjunctivitis Topical adapalene Retinoid |
| title | Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children |
| title_full | Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children |
| title_fullStr | Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children |
| title_full_unstemmed | Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children |
| title_short | Topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children |
| title_sort | topical adapalene for the treatment of follicular conjunctivitis due to periocular molluscum contagiosum in children |
| topic | Periocular molluscum contagiosum Molluscum contagiosum Conjunctivitis Keratoconjunctivitis Topical adapalene Retinoid |
| url | http://www.sciencedirect.com/science/article/pii/S2451993622000810 |
| work_keys_str_mv | AT jonathansyi topicaladapaleneforthetreatmentoffollicularconjunctivitisduetoperiocularmolluscumcontagiosuminchildren AT kelliersatterfield topicaladapaleneforthetreatmentoffollicularconjunctivitisduetoperiocularmolluscumcontagiosuminchildren AT catherineschoi topicaladapaleneforthetreatmentoffollicularconjunctivitisduetoperiocularmolluscumcontagiosuminchildren AT markusdboos topicaladapaleneforthetreatmentoffollicularconjunctivitisduetoperiocularmolluscumcontagiosuminchildren AT michelletcabrera topicaladapaleneforthetreatmentoffollicularconjunctivitisduetoperiocularmolluscumcontagiosuminchildren |