Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer
Early detection of gastric cancer is important. However, rapid growth of gastric cancers that cannot be resected endoscopically occurs even with periodic check-ups. Accordingly, we assessed factors associated with the speed of gastric cancer growth by examining historical endoscopic images. A total...
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MDPI AG
2021-12-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/23/5704 |
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| author | Ko Miura Tadayuki Oshima Akio Tamura Ken Hara Takuya Okugawa Masashi Fukushima Toshihiko Tomita Hirokazu Fukui Hiroto Miwa |
| author_facet | Ko Miura Tadayuki Oshima Akio Tamura Ken Hara Takuya Okugawa Masashi Fukushima Toshihiko Tomita Hirokazu Fukui Hiroto Miwa |
| author_sort | Ko Miura |
| collection | DOAJ |
| description | Early detection of gastric cancer is important. However, rapid growth of gastric cancers that cannot be resected endoscopically occurs even with periodic check-ups. Accordingly, we assessed factors associated with the speed of gastric cancer growth by examining historical endoscopic images. A total of 1996 gastric cancer cases were screened, and characteristics of lesions with slow and rapid growth were assessed. A total of 114 lesions from 114 patients were included in the assessment. Sixty slow-growing and fifty-four rapidly growing gastric cancers were compared. Female sex and incidence of lesions in the lower part of the stomach were significantly less frequent in the rapid-growth group than in the slow-growth group. History of endoscopic treatment tended to be more frequent in the rapid-growth group. Age, body mass index, histology, <i>Helicobacter pylori</i> status, and medications did not differ significantly between groups. Xanthoma was significantly related to rapid growth of gastric cancer, and map-like redness tended to be more frequent in the rapid-growth group in univariate analysis. Xanthoma was significantly related to rapid growth of gastric cancer on multivariate analysis. Further studies are warranted to clarify the pathophysiological mechanisms involved in the speed of gastric cancer growth. |
| first_indexed | 2024-03-10T04:50:02Z |
| format | Article |
| id | doaj.art-1f9a1a38653f488b9375a249193ec256 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T04:50:02Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-1f9a1a38653f488b9375a249193ec2562023-11-23T02:38:09ZengMDPI AGJournal of Clinical Medicine2077-03832021-12-011023570410.3390/jcm10235704Gastric Xanthoma Is Related to the Rapid Growth of Gastric CancerKo Miura0Tadayuki Oshima1Akio Tamura2Ken Hara3Takuya Okugawa4Masashi Fukushima5Toshihiko Tomita6Hirokazu Fukui7Hiroto Miwa8Division of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanDivision of Gastroenterology and Hepatology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, JapanEarly detection of gastric cancer is important. However, rapid growth of gastric cancers that cannot be resected endoscopically occurs even with periodic check-ups. Accordingly, we assessed factors associated with the speed of gastric cancer growth by examining historical endoscopic images. A total of 1996 gastric cancer cases were screened, and characteristics of lesions with slow and rapid growth were assessed. A total of 114 lesions from 114 patients were included in the assessment. Sixty slow-growing and fifty-four rapidly growing gastric cancers were compared. Female sex and incidence of lesions in the lower part of the stomach were significantly less frequent in the rapid-growth group than in the slow-growth group. History of endoscopic treatment tended to be more frequent in the rapid-growth group. Age, body mass index, histology, <i>Helicobacter pylori</i> status, and medications did not differ significantly between groups. Xanthoma was significantly related to rapid growth of gastric cancer, and map-like redness tended to be more frequent in the rapid-growth group in univariate analysis. Xanthoma was significantly related to rapid growth of gastric cancer on multivariate analysis. Further studies are warranted to clarify the pathophysiological mechanisms involved in the speed of gastric cancer growth.https://www.mdpi.com/2077-0383/10/23/5704gastric cancergrowthxanthomatosis |
| spellingShingle | Ko Miura Tadayuki Oshima Akio Tamura Ken Hara Takuya Okugawa Masashi Fukushima Toshihiko Tomita Hirokazu Fukui Hiroto Miwa Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer Journal of Clinical Medicine gastric cancer growth xanthomatosis |
| title | Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer |
| title_full | Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer |
| title_fullStr | Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer |
| title_full_unstemmed | Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer |
| title_short | Gastric Xanthoma Is Related to the Rapid Growth of Gastric Cancer |
| title_sort | gastric xanthoma is related to the rapid growth of gastric cancer |
| topic | gastric cancer growth xanthomatosis |
| url | https://www.mdpi.com/2077-0383/10/23/5704 |
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