BRAF non-V600E more frequently co-occurs with IDH1/2 mutations in adult patients with gliomas than in patients harboring BRAF V600E but without a survival advantage

Abstract Background The effects of BRAF non-V600E and BRAF V600E on the outcomes and the molecular characteristics of adult glioma patients are unknown and need to be explored, although BRAF V600E has been extensively studied in pediatric glioma. Methods Co-occurring mutations and copy number altera...

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Bibliographic Details
Main Authors: Wei Wang, Maode Wang, Haitao Jiang, Tuo Wang, Rong Da
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Neurology
Subjects:
Online Access:https://doi.org/10.1186/s12883-021-02224-6