Exosomes as Actively Targeted Nanocarriers for Cancer Therapy
Yan Wang,1,* Yingru Zhang,1,* Gang Cai,1 Qi Li1,2 1Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China; 2Academy of Integrative Medicine, Shang...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2020-06-01
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| Series: | International Journal of Nanomedicine |
| Subjects: | |
| Online Access: | https://www.dovepress.com/exosomes-as-actively-targeted-nanocarriers-for-cancer-therapy-peer-reviewed-article-IJN |
| _version_ | 1818981492855930880 |
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| author | Wang Y Zhang Y Cai G Li Q |
| author_facet | Wang Y Zhang Y Cai G Li Q |
| author_sort | Wang Y |
| collection | DOAJ |
| description | Yan Wang,1,* Yingru Zhang,1,* Gang Cai,1 Qi Li1,2 1Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China; 2Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li Email qili@shutcm.edu.cnAbstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.Keywords: exosomes, nanocarriers, function, tumor therapy |
| first_indexed | 2024-12-20T17:32:11Z |
| format | Article |
| id | doaj.art-1fa00d8817f940498eb37f83ffd03e1f |
| institution | Directory Open Access Journal |
| issn | 1178-2013 |
| language | English |
| last_indexed | 2024-12-20T17:32:11Z |
| publishDate | 2020-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of Nanomedicine |
| spelling | doaj.art-1fa00d8817f940498eb37f83ffd03e1f2022-12-21T19:31:20ZengDove Medical PressInternational Journal of Nanomedicine1178-20132020-06-01Volume 154257427354583Exosomes as Actively Targeted Nanocarriers for Cancer TherapyWang YZhang YCai GLi QYan Wang,1,* Yingru Zhang,1,* Gang Cai,1 Qi Li1,2 1Department of Medical Oncology & Cancer Institute of Integrative Medicine, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China; 2Academy of Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qi Li Email qili@shutcm.edu.cnAbstract: In recent years, it has been found that exosomes can be used as nanocarriers, which can be used in the treatment of tumors by carrying contents. The exosomes are derived from the secretion of the organism’s own cells and are characterized by a phospholipid bilayer structure and a small particle size. These characteristics guarantee that the exosomes can carry a wide range of tumor drugs, deliver the drug to the cancer, and reduce or eliminate the tumor drug band. The toxic side effects were significantly eliminated; meanwhile, the therapeutic effects of the drug on the tumor were remarkably improved. This paper reviewed the strategies and drugs presented by different scholars for the treatment of tumors based on the drugs carried by exosomes.Keywords: exosomes, nanocarriers, function, tumor therapyhttps://www.dovepress.com/exosomes-as-actively-targeted-nanocarriers-for-cancer-therapy-peer-reviewed-article-IJNexosomesnanocarriersfunctiontumor therapy |
| spellingShingle | Wang Y Zhang Y Cai G Li Q Exosomes as Actively Targeted Nanocarriers for Cancer Therapy International Journal of Nanomedicine exosomes nanocarriers function tumor therapy |
| title | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
| title_full | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
| title_fullStr | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
| title_full_unstemmed | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
| title_short | Exosomes as Actively Targeted Nanocarriers for Cancer Therapy |
| title_sort | exosomes as actively targeted nanocarriers for cancer therapy |
| topic | exosomes nanocarriers function tumor therapy |
| url | https://www.dovepress.com/exosomes-as-actively-targeted-nanocarriers-for-cancer-therapy-peer-reviewed-article-IJN |
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