Diagnosis and treatment of cardiac angiosarcoma
Primary cardiac tumors are very rare in the population. About 20% of it are malignant. The most common type of cardiac malignant tumor is angiosarcoma. This tumor has the ability to infiltrate surrounding tissues and form distant metastases. Angiosarcoma is most often located in the right atrium and...
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2023-06-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/43962 |
| _version_ | 1797800209566138368 |
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| author | Aleksandra Ołownia Jakub Orczyk Agata Tokarzewska Halina Piecewicz-Szczęsna |
| author_facet | Aleksandra Ołownia Jakub Orczyk Agata Tokarzewska Halina Piecewicz-Szczęsna |
| author_sort | Aleksandra Ołownia |
| collection | DOAJ |
| description | Primary cardiac tumors are very rare in the population. About 20% of it are malignant. The most common type of cardiac malignant tumor is angiosarcoma. This tumor has the ability to infiltrate surrounding tissues and form distant metastases. Angiosarcoma is most often located in the right atrium and it mostly attacks men. This neoplasm is difficult to diagnose, because it has no specific symptoms. Patients with this tumor may complain of a chest pain, cardiac arrhythmias, suffocation and distal oedema. The rarity of occurrence and the lack of specyfic symptoms contribute to late diagnosis of the disease and worse prognosis of patients. Angiosarcoma can also be misdiagnosed as pneumonia or more common cardiovascular disease for example coronary artery disease. In advanced stage, this tumor can even lead to myocardial rupture. Various imaging methods are used in the diagnostics of this neoplasm for example: CT, MRI, PET-CT or Echocardiography. Histopathological examinations are less frequently used due to the risk of serious complications like hemothorax. Due to the very uncommon occurrence of the angiosarcoma, guidelines describing treatment of patients with this neoplasm, have not been developed yet. Currently, surgical removal of the tumor (if it is possible), chemiotherapy and radiotherapy are used. Reaserches on the genetic mutations which cause angiosarcoma and the development of appropriate drugs may give patients a chance for more effective treatment in the future
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| first_indexed | 2024-03-13T04:31:39Z |
| format | Article |
| id | doaj.art-1fa01cceb2f846f0bb18d5939aa4a3f6 |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-13T04:31:39Z |
| publishDate | 2023-06-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-1fa01cceb2f846f0bb18d5939aa4a3f62023-06-19T10:46:38ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062023-06-0140110.12775/JEHS.2023.40.01.002Diagnosis and treatment of cardiac angiosarcomaAleksandra Ołownia0Jakub Orczyk1Agata Tokarzewska2Halina Piecewicz-Szczęsna3Student Scientific Association at Department of Epidemiology and Clinical Research Methodology Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080, PolandStudent Scientific Association at Department of Epidemiology and Clinical Research Methodology Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080, PolandStudent Scientific Association at Department of Epidemiology and Clinical Research Methodology Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080, PolandDepartment of Epidemiology and Clinical Research Methodology of the Medical University of Lublin, ul. Radziwiłłowska 11, Lublin 20-080, PolandPrimary cardiac tumors are very rare in the population. About 20% of it are malignant. The most common type of cardiac malignant tumor is angiosarcoma. This tumor has the ability to infiltrate surrounding tissues and form distant metastases. Angiosarcoma is most often located in the right atrium and it mostly attacks men. This neoplasm is difficult to diagnose, because it has no specific symptoms. Patients with this tumor may complain of a chest pain, cardiac arrhythmias, suffocation and distal oedema. The rarity of occurrence and the lack of specyfic symptoms contribute to late diagnosis of the disease and worse prognosis of patients. Angiosarcoma can also be misdiagnosed as pneumonia or more common cardiovascular disease for example coronary artery disease. In advanced stage, this tumor can even lead to myocardial rupture. Various imaging methods are used in the diagnostics of this neoplasm for example: CT, MRI, PET-CT or Echocardiography. Histopathological examinations are less frequently used due to the risk of serious complications like hemothorax. Due to the very uncommon occurrence of the angiosarcoma, guidelines describing treatment of patients with this neoplasm, have not been developed yet. Currently, surgical removal of the tumor (if it is possible), chemiotherapy and radiotherapy are used. Reaserches on the genetic mutations which cause angiosarcoma and the development of appropriate drugs may give patients a chance for more effective treatment in the future https://apcz.umk.pl/JEHS/article/view/43962hearthistopathologyangiosarcomaprimary cardiac tumormalignant tumorcardiology |
| spellingShingle | Aleksandra Ołownia Jakub Orczyk Agata Tokarzewska Halina Piecewicz-Szczęsna Diagnosis and treatment of cardiac angiosarcoma Journal of Education, Health and Sport heart histopathology angiosarcoma primary cardiac tumor malignant tumor cardiology |
| title | Diagnosis and treatment of cardiac angiosarcoma |
| title_full | Diagnosis and treatment of cardiac angiosarcoma |
| title_fullStr | Diagnosis and treatment of cardiac angiosarcoma |
| title_full_unstemmed | Diagnosis and treatment of cardiac angiosarcoma |
| title_short | Diagnosis and treatment of cardiac angiosarcoma |
| title_sort | diagnosis and treatment of cardiac angiosarcoma |
| topic | heart histopathology angiosarcoma primary cardiac tumor malignant tumor cardiology |
| url | https://apcz.umk.pl/JEHS/article/view/43962 |
| work_keys_str_mv | AT aleksandraołownia diagnosisandtreatmentofcardiacangiosarcoma AT jakuborczyk diagnosisandtreatmentofcardiacangiosarcoma AT agatatokarzewska diagnosisandtreatmentofcardiacangiosarcoma AT halinapiecewiczszczesna diagnosisandtreatmentofcardiacangiosarcoma |