Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report
Abstract Background Chlamydia abortus is generally considered to cause abortion, stillbirth, and gestational sepsis in pregnant women, but it’s rare in bloodstream infection and pneumonia. Case presentation We present details of a patient with bloodstream infection and pneumonia caused by Chlamydia...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-02-01
|
| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-022-07158-z |
| _version_ | 1818491482551615488 |
|---|---|
| author | Changjun Zhu Minjie Lv Jianling Huang Changwen Zhang Lixu Xie Tianming Gao Bo Han Wenjing Wang Ganzhu Feng |
| author_facet | Changjun Zhu Minjie Lv Jianling Huang Changwen Zhang Lixu Xie Tianming Gao Bo Han Wenjing Wang Ganzhu Feng |
| author_sort | Changjun Zhu |
| collection | DOAJ |
| description | Abstract Background Chlamydia abortus is generally considered to cause abortion, stillbirth, and gestational sepsis in pregnant women, but it’s rare in bloodstream infection and pneumonia. Case presentation We present details of a patient with bloodstream infection and pneumonia caused by Chlamydia abortus. Both blood next-generation sequencing (NGS) and sputum NGS indicate Chlamydia abortus infection. The patient received intravenous infusion of piperacillin sodium and tazobactam sodium (4.5 g/8 h) and moxifloxacin (0.4 g/d) and oral oseltamivir (75 mg/day). Within one month of follow-up, the patient's clinical symptoms were significantly improved, and all laboratory parameters showed no marked abnormality. However, chest computer tomography (CT) showed the inflammation wasn’t completely absorbed. And we are still following up. Conclusions Chlamydia abortus can cause pneumonia in humans. NGS has the particular advantage of quickly and accurately identifying the infection of such rare pathogens. Pneumonia is generally not life-threatening, and has a good prognosis with appropriate treatment. However, Chlamydia infection can lead to serious visceral complications which clinicians should pay attention to. |
| first_indexed | 2024-12-10T17:31:24Z |
| format | Article |
| id | doaj.art-1fa657c2207241fd85e56adad0ca7a2d |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-10T17:31:24Z |
| publishDate | 2022-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-1fa657c2207241fd85e56adad0ca7a2d2022-12-22T01:39:40ZengBMCBMC Infectious Diseases1471-23342022-02-012211710.1186/s12879-022-07158-zBloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case reportChangjun Zhu0Minjie Lv1Jianling Huang2Changwen Zhang3Lixu Xie4Tianming Gao5Bo Han6Wenjing Wang7Ganzhu Feng8Department of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityDepartment of Respiratory Medicine, the Second Affiliated Hospital of Nanjing Medical UniversityAbstract Background Chlamydia abortus is generally considered to cause abortion, stillbirth, and gestational sepsis in pregnant women, but it’s rare in bloodstream infection and pneumonia. Case presentation We present details of a patient with bloodstream infection and pneumonia caused by Chlamydia abortus. Both blood next-generation sequencing (NGS) and sputum NGS indicate Chlamydia abortus infection. The patient received intravenous infusion of piperacillin sodium and tazobactam sodium (4.5 g/8 h) and moxifloxacin (0.4 g/d) and oral oseltamivir (75 mg/day). Within one month of follow-up, the patient's clinical symptoms were significantly improved, and all laboratory parameters showed no marked abnormality. However, chest computer tomography (CT) showed the inflammation wasn’t completely absorbed. And we are still following up. Conclusions Chlamydia abortus can cause pneumonia in humans. NGS has the particular advantage of quickly and accurately identifying the infection of such rare pathogens. Pneumonia is generally not life-threatening, and has a good prognosis with appropriate treatment. However, Chlamydia infection can lead to serious visceral complications which clinicians should pay attention to.https://doi.org/10.1186/s12879-022-07158-zBloodstream infectionPneumoniaChlamydia abortusCase report |
| spellingShingle | Changjun Zhu Minjie Lv Jianling Huang Changwen Zhang Lixu Xie Tianming Gao Bo Han Wenjing Wang Ganzhu Feng Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report BMC Infectious Diseases Bloodstream infection Pneumonia Chlamydia abortus Case report |
| title | Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report |
| title_full | Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report |
| title_fullStr | Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report |
| title_full_unstemmed | Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report |
| title_short | Bloodstream infection and pneumonia caused by Chlamydia abortus infection in China: a case report |
| title_sort | bloodstream infection and pneumonia caused by chlamydia abortus infection in china a case report |
| topic | Bloodstream infection Pneumonia Chlamydia abortus Case report |
| url | https://doi.org/10.1186/s12879-022-07158-z |
| work_keys_str_mv | AT changjunzhu bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT minjielv bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT jianlinghuang bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT changwenzhang bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT lixuxie bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT tianminggao bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT bohan bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT wenjingwang bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport AT ganzhufeng bloodstreaminfectionandpneumoniacausedbychlamydiaabortusinfectioninchinaacasereport |