Unconventional Functions of Amino Acid Transporters: Role in Macropinocytosis (SLC38A5/SLC38A3) and Diet-Induced Obesity/Metabolic Syndrome (SLC6A19/SLC6A14/SLC6A6)

Unconventional Functions of Amino Acid Transporters: Role in Macropinocytosis (SLC38A5/SLC38A3) and Diet-Induced Obesity/Metabolic Syndrome (SLC6A19/SLC6A14/SLC6A6)

Amino acid transporters are expressed in mammalian cells not only in the plasma membrane but also in intracellular membranes. The conventional function of these transporters is to transfer their amino acid substrates across the lipid bilayer; the direction of the transfer is dictated by the combined...

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Bibliographic Details
Main Authors: Yangzom D. Bhutia, Marilyn Mathew, Sathish Sivaprakasam, Sabarish Ramachandran, Vadivel Ganapathy
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Biomolecules
Subjects:
macropinocytosis
amino acid-dependent Na<sup>+</sup>/H<sup>+</sup> exchange
SLC38A5/SLC38A3
enteroendocrine cell
gut hormones
insulin signaling
Online Access:https://www.mdpi.com/2218-273X/12/2/235

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