Chronic exercise improves hepatic acylcarnitine handling
Summary: Exercise mediates tissue metabolic function through direct and indirect adaptations to acylcarnitine (AC) metabolism, but the exact mechanisms are unclear. We found that circulating medium-chain acylcarnitines (AC) (C12-C16) are lower in active/endurance trained human subjects compared to s...
Main Authors: | Diego Hernández-Saavedra, J. Matthew Hinkley, Lisa A. Baer, Kelsey M. Pinckard, Pablo Vidal, Shinsuke Nirengi, Andrea M. Brennan, Emily Y. Chen, Niven R. Narain, Valerie Bussberg, Vladimir V. Tolstikov, Michael A. Kiebish, Christina Markunas, Olga Ilkayeva, Bret H. Goodpaster, Christopher B. Newgard, Laurie J. Goodyear, Paul M. Coen, Kristin I. Stanford |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2024-03-01
|
Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224003043 |
Similar Items
-
Brown adipose tissue and aging: A potential role for exercise
by: Shinsuke Nirengi, et al.
Published: (2023-07-01) -
Current Status of Metabolomic Biomarker Discovery: Impact of Study Design and Demographic Characteristics
by: Vladimir Tolstikov, et al.
Published: (2020-05-01) -
Transplantation of Brown Adipose Tissue with the Ability of Converting Omega-6 to Omega-3 Polyunsaturated Fatty Acids Counteracts High-Fat-Induced Metabolic Abnormalities in Mice
by: Tadataka Tsuji, et al.
Published: (2022-05-01) -
Circulating long chain acylcarnitines and outcomes in diabetic heart failure: an HF-ACTION clinical trial substudy
by: Lauren K. Truby, et al.
Published: (2021-08-01) -
Metabolomic effects of androgen deprivation therapy treatment for prostate cancer
by: Jen‐Tsan Chi, et al.
Published: (2020-06-01)