Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report
Introduction. During the last few years, intravenous lipid emulsions have been effectively used in treatment of acute poisonings with lipophilic substances, including verapamil. Case report. A 37-year-old women presented 1 hour after ingestion of 2.8 g verapamil with hypotension and complet...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Military Health Department, Ministry of Defance, Serbia
2017-01-01
|
Series: | Vojnosanitetski Pregled |
Subjects: | |
Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600010V.pdf |
_version_ | 1818536143909552128 |
---|---|
author | Vuković-Ercegović Gordana Perković-Vukčević Nataša Đorđević Snežana Šegrt Zoran Potrebić Olivera Janković Snežana R. Jović-Stošić Jasmina Marinković Nadica |
author_facet | Vuković-Ercegović Gordana Perković-Vukčević Nataša Đorđević Snežana Šegrt Zoran Potrebić Olivera Janković Snežana R. Jović-Stošić Jasmina Marinković Nadica |
author_sort | Vuković-Ercegović Gordana |
collection | DOAJ |
description | Introduction. During the last few years, intravenous lipid emulsions have
been effectively used in treatment of acute poisonings with lipophilic
substances, including verapamil. Case report. A 37-year-old women presented 1
hour after ingestion of 2.8 g verapamil with hypotension and complete heart
block. Because of the applied standard therapy failure and further patients
impairment, Intralipid® 20% was used. Sinus rhythm was restored, arterial
blood pressure increased and verapamile concentrations, both total and free
decreased. Conclusion. Intravenous lipid emulsion can be important in
treatment of severe acute intoxication and cardiotoxicity caused by
verapamil. |
first_indexed | 2024-12-11T18:34:09Z |
format | Article |
id | doaj.art-1fa8a6040ef34b3d8e44bd4bca4fa688 |
institution | Directory Open Access Journal |
issn | 0042-8450 2406-0720 |
language | English |
last_indexed | 2024-12-11T18:34:09Z |
publishDate | 2017-01-01 |
publisher | Military Health Department, Ministry of Defance, Serbia |
record_format | Article |
series | Vojnosanitetski Pregled |
spelling | doaj.art-1fa8a6040ef34b3d8e44bd4bca4fa6882022-12-22T00:54:49ZengMilitary Health Department, Ministry of Defance, SerbiaVojnosanitetski Pregled0042-84502406-07202017-01-0174327828110.2298/VSP150901010V0042-84501600010VSuccessful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case reportVuković-Ercegović Gordana0Perković-Vukčević Nataša1Đorđević Snežana2Šegrt Zoran3Potrebić Olivera4Janković Snežana R.5Jović-Stošić Jasmina6Marinković Nadica7Military Medical Academy, National Poison Control Center, BelgradeMilitary Medical Academy, National Poison Control Center, BelgradeMilitary Medical Academy, National Poison Control Center, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, National Poison Control Center, BelgradeMilitary Medical Academy, Institute for Scientific Information, BelgradeMilitary Medical Academy, National Poison Control Center, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic Medicine, BelgradeIntroduction. During the last few years, intravenous lipid emulsions have been effectively used in treatment of acute poisonings with lipophilic substances, including verapamil. Case report. A 37-year-old women presented 1 hour after ingestion of 2.8 g verapamil with hypotension and complete heart block. Because of the applied standard therapy failure and further patients impairment, Intralipid® 20% was used. Sinus rhythm was restored, arterial blood pressure increased and verapamile concentrations, both total and free decreased. Conclusion. Intravenous lipid emulsion can be important in treatment of severe acute intoxication and cardiotoxicity caused by verapamil.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600010V.pdfpoisoningsuicideverapamilcalcium channel blockersheart blockfat emulsions, intravenoustreatment outcome |
spellingShingle | Vuković-Ercegović Gordana Perković-Vukčević Nataša Đorđević Snežana Šegrt Zoran Potrebić Olivera Janković Snežana R. Jović-Stošić Jasmina Marinković Nadica Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report Vojnosanitetski Pregled poisoning suicide verapamil calcium channel blockers heart block fat emulsions, intravenous treatment outcome |
title | Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report |
title_full | Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report |
title_fullStr | Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report |
title_full_unstemmed | Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report |
title_short | Successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning: A case report |
title_sort | successful usage of intravenous lipid emulsion in treatment of acute verapamil poisoning a case report |
topic | poisoning suicide verapamil calcium channel blockers heart block fat emulsions, intravenous treatment outcome |
url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600010V.pdf |
work_keys_str_mv | AT vukovicercegovicgordana successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT perkovicvukcevicnatasa successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT đorđevicsnezana successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT segrtzoran successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT potrebicolivera successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT jankovicsnezanar successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT jovicstosicjasmina successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport AT marinkovicnadica successfulusageofintravenouslipidemulsionintreatmentofacuteverapamilpoisoningacasereport |