My cooperation with Gerta Vrbová – Chance and necessity

An inspiring scientific cooperation has come to an end, when Gerta Vrbová, an internationally renowned researcher in the field of neuromuscular interactions, passed away on October 2, 2020. Comparative EMG studies had led Gerta to suggest that different contractile properties of fast- and slow-twitc...

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Main Author: Dirk Pette
Format: Article
Language:English
Published: PAGEPress Publications 2021-01-01
Series:European Journal of Translational Myology
Subjects:
Online Access:https://www.pagepressjournals.org/index.php/bam/article/view/9585
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author Dirk Pette
author_facet Dirk Pette
author_sort Dirk Pette
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description An inspiring scientific cooperation has come to an end, when Gerta Vrbová, an internationally renowned researcher in the field of neuromuscular interactions, passed away on October 2, 2020. Comparative EMG studies had led Gerta to suggest that different contractile properties of fast- and slow-twitch muscle fibers relate to specific firing patterns of their motoneurones. In support of her hypothesis, long term stimulation of fast-twitch muscles with a stimulus pattern resembling that of slow motoneurones, were shown to induce a pronounced fast-to-slow shift in contractile properties. In our cooperation which started in 1970, and also in cooperation with others, Gerta's experiment proved to be an ideal model for the study of neurally controlled changes in phenotype characteristics at various levels of molecular and cellular organization, their time courses and ranges. It has become most important in basic research on the adaptive potential or plasticity of muscle.
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spelling doaj.art-1faa834633074606b2906bd778d14be62022-12-21T23:28:00ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602021-01-0110.4081/ejtm.2020.9585My cooperation with Gerta Vrbová – Chance and necessityDirk Pette0Department of Biology, University of Konstanz, KonstanzAn inspiring scientific cooperation has come to an end, when Gerta Vrbová, an internationally renowned researcher in the field of neuromuscular interactions, passed away on October 2, 2020. Comparative EMG studies had led Gerta to suggest that different contractile properties of fast- and slow-twitch muscle fibers relate to specific firing patterns of their motoneurones. In support of her hypothesis, long term stimulation of fast-twitch muscles with a stimulus pattern resembling that of slow motoneurones, were shown to induce a pronounced fast-to-slow shift in contractile properties. In our cooperation which started in 1970, and also in cooperation with others, Gerta's experiment proved to be an ideal model for the study of neurally controlled changes in phenotype characteristics at various levels of molecular and cellular organization, their time courses and ranges. It has become most important in basic research on the adaptive potential or plasticity of muscle.https://www.pagepressjournals.org/index.php/bam/article/view/9585cardiomyoplastychronic electrical stimulationmuscle plasticityneural controlskeletal muscle fiber types
spellingShingle Dirk Pette
My cooperation with Gerta Vrbová – Chance and necessity
European Journal of Translational Myology
cardiomyoplasty
chronic electrical stimulation
muscle plasticity
neural control
skeletal muscle fiber types
title My cooperation with Gerta Vrbová – Chance and necessity
title_full My cooperation with Gerta Vrbová – Chance and necessity
title_fullStr My cooperation with Gerta Vrbová – Chance and necessity
title_full_unstemmed My cooperation with Gerta Vrbová – Chance and necessity
title_short My cooperation with Gerta Vrbová – Chance and necessity
title_sort my cooperation with gerta vrbova chance and necessity
topic cardiomyoplasty
chronic electrical stimulation
muscle plasticity
neural control
skeletal muscle fiber types
url https://www.pagepressjournals.org/index.php/bam/article/view/9585
work_keys_str_mv AT dirkpette mycooperationwithgertavrbovachanceandnecessity