Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment

Breast Cancer Organoids Model Patient-Specific Response to Drug Treatment

Tumor organoids are tridimensional cell culture systems that are generated in vitro from surgically resected patients’ tumors. They can be propagated in culture maintaining several features of the tumor of origin, including cellular and genetic heterogeneity, thus representing a promising tool for p...

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Bibliographic Details
Main Authors: Elena Campaner, Alessandro Zannini, Mariangela Santorsola, Deborah Bonazza, Cristina Bottin, Valeria Cancila, Claudio Tripodo, Marina Bortul, Fabrizio Zanconati, Stefan Schoeftner, Giannino Del Sal
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
patient-derived tumor organoids
breast cancer
heterogeneity
drug testing
mechanotransduction
YAP
Online Access:https://www.mdpi.com/2072-6694/12/12/3869

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