Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis

Patients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa...

Full description

Bibliographic Details
Main Authors: E. V. Esaulenko, O. E. Nikitina, N. V. Dunaeva, A. N. Uskov, T. L. Mogilevets
Format: Article
Language:Russian
Published: Journal Infectology 2014-09-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/39
_version_ 1797702054103220224
author E. V. Esaulenko
O. E. Nikitina
N. V. Dunaeva
A. N. Uskov
T. L. Mogilevets
author_facet E. V. Esaulenko
O. E. Nikitina
N. V. Dunaeva
A. N. Uskov
T. L. Mogilevets
author_sort E. V. Esaulenko
collection DOAJ
description Patients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa) over the course of 12 weeks. During therapy alanine aminotransferase, aspartate aminotransferase, bilirubin and gamma-glutamyl transpeptidase levels decreased. Urdoxa demonstrated good tolerance, efficacy and no visible side effects. Thus, Urdoxa could be used in treatment of chronic viral hepatitis with cytolytic and cholestatic syndromes.
first_indexed 2024-03-12T04:45:40Z
format Article
id doaj.art-1fadd4cb9a1a4c93809afcd711e44447
institution Directory Open Access Journal
issn 2072-6732
language Russian
last_indexed 2024-03-12T04:45:40Z
publishDate 2014-09-01
publisher Journal Infectology
record_format Article
series Журнал инфектологии
spelling doaj.art-1fadd4cb9a1a4c93809afcd711e444472023-09-03T09:28:16ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0133424510.22625/2072-6732-2011-3-3-42-4553Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitisE. V. Esaulenko0O. E. Nikitina1N. V. Dunaeva2A. N. Uskov3T. L. Mogilevets4Санкт-Петербургская государственная педиатрическая медицинская академия, Санкт-ПетербургНаучно-исследовательский институт гриппа, Санкт-ПетербургНаучно-исследовательский институт гриппа, Санкт-ПетербургНаучно-исследовательский институт детских инфекций ФМБА России, Санкт-ПетербургНовгородский государственный университет им. Ярослава Мудрого, Великий НовгородPatients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa) over the course of 12 weeks. During therapy alanine aminotransferase, aspartate aminotransferase, bilirubin and gamma-glutamyl transpeptidase levels decreased. Urdoxa demonstrated good tolerance, efficacy and no visible side effects. Thus, Urdoxa could be used in treatment of chronic viral hepatitis with cytolytic and cholestatic syndromes.https://journal.niidi.ru/jofin/article/view/39хронический вирусный гепатитурсодеоксихолевая кислотаурдокса
spellingShingle E. V. Esaulenko
O. E. Nikitina
N. V. Dunaeva
A. N. Uskov
T. L. Mogilevets
Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
Журнал инфектологии
хронический вирусный гепатит
урсодеоксихолевая кислота
урдокса
title Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
title_full Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
title_fullStr Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
title_full_unstemmed Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
title_short Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
title_sort clinical experience with ursodeoxycholic acid urdoxa in complex therapy of chronic viral hepatitis
topic хронический вирусный гепатит
урсодеоксихолевая кислота
урдокса
url https://journal.niidi.ru/jofin/article/view/39
work_keys_str_mv AT evesaulenko clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis
AT oenikitina clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis
AT nvdunaeva clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis
AT anuskov clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis
AT tlmogilevets clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis