Clinical case report: сonservative treatment of nodular adenomyosis
The article describes the clinical case of the nodular form of adenomyosis, first detected in a patient at the age of 16 years after another appeal to a gynecologist in connection with pronounced prolonged dysmenorrhea with ultrasound of a small pelvis. After the diagnosis of “Nodular form of adenom...
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| Format: | Article |
| Language: | English |
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Publishing House TRILIST
2018-04-01
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| Series: | Репродуктивная эндокринология |
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| Online Access: | http://reproduct-endo.com/article/view/131195 |
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| author | Н. Ф. Захаренко Н. В. Коваленко И. П. Маноляк |
| author_facet | Н. Ф. Захаренко Н. В. Коваленко И. П. Маноляк |
| author_sort | Н. Ф. Захаренко |
| collection | DOAJ |
| description | The article describes the clinical case of the nodular form of adenomyosis, first detected in a patient at the age of 16 years after another appeal to a gynecologist in connection with pronounced prolonged dysmenorrhea with ultrasound of a small pelvis. After the diagnosis of “Nodular form of adenomyosis”, the patient received 6 injections of triptorelin acetate 3.62 mg, resulting in an adenomyosis node decreased in size from 72 x 68 mm to 31 x 29 mm. Taking into account the developed side effects (aches in bones, hot flushes, weakness, tachycardia), therapy with triptorelin was discontinued. Clinical efficacy persisted for 6 months, after which painful menstruation resumed.
Two years later, the patient was urgently transferred to the gynecological department of the Kyiv City Clinical Hospital No. 9 with severe manifestations of dysmenorrhea. With ultrasound of the pelvic organs, an endometrioid node in the uterus measuring 50 x 46 mm was found. The patient was recommended receiving Visanne (dienogest) in a dose of 2 mg, which she took 1 year and 10 months, being under constant supervision of the clinic’s specialists. The unauthorized break in treatment, which the patient explained with good health, provoked the resumption of painful symptoms. Visanne was continued for 2 years, as a result of which the endometrioid node decreased to 21.0 x 16.7 mm.
In April 2017, in connection with the patient’s marriage and the desire to become pregnant, the reception of the dienogest was canceled. It is proposed to take a plant complex of antiproliferative action containing indole-3-carbinol 200 mg and green tea extract 82 mg. After 8 months, the patient was diagnosed with a pregnancy at 4 weeks, against which the adenomyosis node decreased to 18.1 x 11.1 mm. The results of the first two ultrasound screenings of the fetus in the gestation period of 13 and 18 weeks are described. There were no deviations in fetal development, and the endometriosis focus in the uterus was not clearly visualized at the first screening.
The importance of the problem of secondary dysmenorrhea on the background of endometriosis, the establishment of a timely diagnosis and the choice of the right treatment tactics on which the future reproductive health of a teenage girl directly depends. |
| first_indexed | 2024-12-13T19:43:37Z |
| format | Article |
| id | doaj.art-1fb1b27e0d1245479144eeebd310582c |
| institution | Directory Open Access Journal |
| issn | 2309-4117 2411-1295 |
| language | English |
| last_indexed | 2024-12-13T19:43:37Z |
| publishDate | 2018-04-01 |
| publisher | Publishing House TRILIST |
| record_format | Article |
| series | Репродуктивная эндокринология |
| spelling | doaj.art-1fb1b27e0d1245479144eeebd310582c2022-12-21T23:33:36ZengPublishing House TRILISTРепродуктивная эндокринология2309-41172411-12952018-04-0140444810.18370/2309-4117.2018.40.44-48122027Clinical case report: сonservative treatment of nodular adenomyosisН. Ф. Захаренко0https://orcid.org/0000-0003-2934-3157Н. В. Коваленко1https://orcid.org/0000-0002-6787-0559И. П. Маноляк2SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”Kyiv City Clinical Hospital No. 9SI “O.M. Lukyanova Institute of Pediatrics, Obstetrics and Gynecology of the NAMS of Ukraine”The article describes the clinical case of the nodular form of adenomyosis, first detected in a patient at the age of 16 years after another appeal to a gynecologist in connection with pronounced prolonged dysmenorrhea with ultrasound of a small pelvis. After the diagnosis of “Nodular form of adenomyosis”, the patient received 6 injections of triptorelin acetate 3.62 mg, resulting in an adenomyosis node decreased in size from 72 x 68 mm to 31 x 29 mm. Taking into account the developed side effects (aches in bones, hot flushes, weakness, tachycardia), therapy with triptorelin was discontinued. Clinical efficacy persisted for 6 months, after which painful menstruation resumed. Two years later, the patient was urgently transferred to the gynecological department of the Kyiv City Clinical Hospital No. 9 with severe manifestations of dysmenorrhea. With ultrasound of the pelvic organs, an endometrioid node in the uterus measuring 50 x 46 mm was found. The patient was recommended receiving Visanne (dienogest) in a dose of 2 mg, which she took 1 year and 10 months, being under constant supervision of the clinic’s specialists. The unauthorized break in treatment, which the patient explained with good health, provoked the resumption of painful symptoms. Visanne was continued for 2 years, as a result of which the endometrioid node decreased to 21.0 x 16.7 mm. In April 2017, in connection with the patient’s marriage and the desire to become pregnant, the reception of the dienogest was canceled. It is proposed to take a plant complex of antiproliferative action containing indole-3-carbinol 200 mg and green tea extract 82 mg. After 8 months, the patient was diagnosed with a pregnancy at 4 weeks, against which the adenomyosis node decreased to 18.1 x 11.1 mm. The results of the first two ultrasound screenings of the fetus in the gestation period of 13 and 18 weeks are described. There were no deviations in fetal development, and the endometriosis focus in the uterus was not clearly visualized at the first screening. The importance of the problem of secondary dysmenorrhea on the background of endometriosis, the establishment of a timely diagnosis and the choice of the right treatment tactics on which the future reproductive health of a teenage girl directly depends.http://reproduct-endo.com/article/view/131195adenomyosisdysmenorrheaendometriosisadolescent periodvisannedienogest |
| spellingShingle | Н. Ф. Захаренко Н. В. Коваленко И. П. Маноляк Clinical case report: сonservative treatment of nodular adenomyosis Репродуктивная эндокринология adenomyosis dysmenorrhea endometriosis adolescent period visanne dienogest |
| title | Clinical case report: сonservative treatment of nodular adenomyosis |
| title_full | Clinical case report: сonservative treatment of nodular adenomyosis |
| title_fullStr | Clinical case report: сonservative treatment of nodular adenomyosis |
| title_full_unstemmed | Clinical case report: сonservative treatment of nodular adenomyosis |
| title_short | Clinical case report: сonservative treatment of nodular adenomyosis |
| title_sort | clinical case report сonservative treatment of nodular adenomyosis |
| topic | adenomyosis dysmenorrhea endometriosis adolescent period visanne dienogest |
| url | http://reproduct-endo.com/article/view/131195 |
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