G-Quadruplex-Forming Aptamers—Characteristics, Applications, and Perspectives
G-quadruplexes constitute a unique class of nucleic acid structures formed by G-rich oligonucleotides of DNA- or RNA-type. Depending on their chemical nature, loops length, and localization in the sequence or structure molecularity, G-quadruplexes are highly polymorphic structures showing various fo...
Main Authors: | Carolina Roxo, Weronika Kotkowiak, Anna Pasternak |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-10-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/24/20/3781 |
Similar Items
-
Beyond G-Quadruplexes—The Effect of Junction with Additional Structural Motifs on Aptamers Properties
by: Weronika Kotkowiak, et al.
Published: (2021-09-01) -
Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative
by: Weronika Kotkowiak, et al.
Published: (2018-03-01) -
The Regioselective Conjugation of the 15-nt Thrombin Aptamer with an Optimized Tripeptide Sequence Greatly Increases the Anticoagulant Activity of the Aptamer
by: Irina V. Varizhuk, et al.
Published: (2023-02-01) -
A Comprehensive Analysis of the Thrombin Binding Aptamer Containing Functionalized Pyrrolo-2’-deoxycytidines
by: Weronika Kotkowiak, et al.
Published: (2021-12-01) -
G4 Matters—The Influence of G-Quadruplex Structural Elements on the Antiproliferative Properties of G-Rich Oligonucleotides
by: Carolina Roxo, et al.
Published: (2021-05-01)