Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe

Summary: This is the first report comparing EULAR and national treatment recommendations for PsA patients across Europe, and the first this decade to compare ASAS-EULAR and national treatment recommendations in axSpA patients. An electronic survey was completed from October 2021–April 2022 by rheuma...

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Main Authors: Brigitte Michelsen, Mikkel Østergaard, Michael John Nissen, Adrian Ciurea, Burkhard Möller, Lykke Midtbøll Ørnbjerg, Jakub Zavada, Bente Glintborg, Alan MacDonald, Karin Laas, Dan Nordström, Bjorn Gudbjornsson, Florenzo Iannone, Pasoon Hellmand, Tore Kristian Kvien, Ana Maria Rodrigues, Catalin Codreanu, Ziga Rotar, Isabel Castrejón Fernández, Johan Karlsson Wallman, Jiri Vencovsky, Anne Gitte Loft, Maureen Heddle, Sigrid Vorobjov, Anna-Mari Hokkanen, Gerdur Gröndal, Marco Sebastiani, Marleen van de Sande, Eirik Klami Kristianslund, Maria José Santos, Corina Mogosan, Matija Tomsic, Federico Díaz-González, Daniela Di Giuseppe, Merete Lund Hetland
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:The Lancet Regional Health. Europe
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666776223001254
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author Brigitte Michelsen
Mikkel Østergaard
Michael John Nissen
Adrian Ciurea
Burkhard Möller
Lykke Midtbøll Ørnbjerg
Jakub Zavada
Bente Glintborg
Alan MacDonald
Karin Laas
Dan Nordström
Bjorn Gudbjornsson
Florenzo Iannone
Pasoon Hellmand
Tore Kristian Kvien
Ana Maria Rodrigues
Catalin Codreanu
Ziga Rotar
Isabel Castrejón Fernández
Johan Karlsson Wallman
Jiri Vencovsky
Anne Gitte Loft
Maureen Heddle
Sigrid Vorobjov
Anna-Mari Hokkanen
Gerdur Gröndal
Marco Sebastiani
Marleen van de Sande
Eirik Klami Kristianslund
Maria José Santos
Corina Mogosan
Matija Tomsic
Federico Díaz-González
Daniela Di Giuseppe
Merete Lund Hetland
author_facet Brigitte Michelsen
Mikkel Østergaard
Michael John Nissen
Adrian Ciurea
Burkhard Möller
Lykke Midtbøll Ørnbjerg
Jakub Zavada
Bente Glintborg
Alan MacDonald
Karin Laas
Dan Nordström
Bjorn Gudbjornsson
Florenzo Iannone
Pasoon Hellmand
Tore Kristian Kvien
Ana Maria Rodrigues
Catalin Codreanu
Ziga Rotar
Isabel Castrejón Fernández
Johan Karlsson Wallman
Jiri Vencovsky
Anne Gitte Loft
Maureen Heddle
Sigrid Vorobjov
Anna-Mari Hokkanen
Gerdur Gröndal
Marco Sebastiani
Marleen van de Sande
Eirik Klami Kristianslund
Maria José Santos
Corina Mogosan
Matija Tomsic
Federico Díaz-González
Daniela Di Giuseppe
Merete Lund Hetland
author_sort Brigitte Michelsen
collection DOAJ
description Summary: This is the first report comparing EULAR and national treatment recommendations for PsA patients across Europe, and the first this decade to compare ASAS-EULAR and national treatment recommendations in axSpA patients. An electronic survey was completed from October 2021–April 2022 by rheumatologists in 15 European countries. One and four countries followed all EULAR and ASAS-EULAR recommendations, respectively. Five countries had no national treatment recommendations for PsA and/or axSpA, but followed other regulations. In several countries, national treatment recommendations predated the most recent EULAR/ASAS-EULAR recommendations. Entry criteria for starting biologic/targeted synthetic disease-modifying anti-rheumatic drugs varied considerably. In several countries, for PsA patients with significant skin involvement, interleukin-17 inhibitors were not given preference. The positioning of Janus Kinase inhibitors differed and Phosphodiesterase-4 inhibitors were not in use/reimbursed in most countries. This study may motivate European countries to update their national treatment recommendations, to align them better with the latest international recommendations.
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spelling doaj.art-1fb7ead5c4ae4f17b05c44782857a4ee2023-08-06T04:38:28ZengElsevierThe Lancet Regional Health. Europe2666-77622023-10-0133100706Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across EuropeBrigitte Michelsen0Mikkel Østergaard1Michael John Nissen2Adrian Ciurea3Burkhard Möller4Lykke Midtbøll Ørnbjerg5Jakub Zavada6Bente Glintborg7Alan MacDonald8Karin Laas9Dan Nordström10Bjorn Gudbjornsson11Florenzo Iannone12Pasoon Hellmand13Tore Kristian Kvien14Ana Maria Rodrigues15Catalin Codreanu16Ziga Rotar17Isabel Castrejón Fernández18Johan Karlsson Wallman19Jiri Vencovsky20Anne Gitte Loft21Maureen Heddle22Sigrid Vorobjov23Anna-Mari Hokkanen24Gerdur Gröndal25Marco Sebastiani26Marleen van de Sande27Eirik Klami Kristianslund28Maria José Santos29Corina Mogosan30Matija Tomsic31Federico Díaz-González32Daniela Di Giuseppe33Merete Lund Hetland34Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway; Research Unit, Sørlandet Hospital, Kristiansand, Norway; Corresponding author. Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark.Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, DenmarkDepartment of Rheumatology, Geneva University Hospital, Geneva, SwitzerlandDepartment of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, SwitzerlandDepartment of Rheumatology and Immunology, Inselspital - University Hospital Bern, SwitzerlandCopenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, DenmarkInstitute of Rheumatology, Prague, Czech Republic; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech RepublicDepartment of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, DenmarkNHS Grampian, Scotland, UKDepartment of Rheumatology, East-Tallinn Central Hospital, Tallinn, EstoniaDepartments of Medicine and Rheumatology, Helsinki University Hospital, Helsinki, FinlandCentre for Rheumatology Research, Landspitali University Hospital, Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Reykjavik, IcelandRheumatology Unit, DETO, University of Bari, ItalyDepartment of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Amsterdam, the NetherlandsCenter for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, NorwayReuma.pt, Sociedade Portuguesa de Reumatologia, Lisbon, Portugal; EpiDoC Unit, Nova Medical School, Lisbon, Portugal; Rheumatology Unit, Hospital dos Lusíadas, Lisbon, PortugalCenter for Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, Universitiy of Ljubljana, Ljubljana, SloveniaDepartment of Rheumatology, Hospital General, Universitario Gregorio Marañón, Madrid, Spain; Faculty of Medicine, Complutense University of Madrid, SpainDepartment of Clinical Sciences Lund, Rheumatology, Skåne University Hospital, Lund University, Lund, SwedenInstitute of Rheumatology, Prague, Czech Republic; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech RepublicDepartment of Rheumatology, Aarhus University Hospital, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, DenmarkAberdeen Centre for Arthritis and Musculoskeletal Health (Epidemiology Group), University of Aberdeen, UKNational Institute for Health Development, Tallinn, EstoniaDepartment of Medicine, Helsinki University and Helsinki University Hospital, Helsinki, FinlandCentre for Rheumatology Research, Landspitali University Hospital, Reykjavik, IcelandRheumatology Unit, University of Modena and Reggio Emilia, Modena, ItalyDepartment of Rheumatology & Clinical Immunology and Department of Experimental Immunology, Amsterdam UMC, University of Amsterdam, Amsterdam Institute for Infection & Immunity, Amsterdam, the Netherlands; Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, the NetherlandsCenter for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, NorwayDepartment of Rheumatology, Hospital Garcia de Orta, Almada, Portugal; Instituto Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, PortugalCenter for Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, Universitiy of Ljubljana, Ljubljana, SloveniaDepartment of Internal Medicine, Dermatology and Psychiatry, Universidad de la Laguna, La Laguna, Spain; Rheumatology Service, Hospital Universitario de Canarias, La Laguna, SpainClinical Epidemiology Division, Department of Medicine Solna, Karolinska Institutet, Stockholm, SwedenCopenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, DenmarkSummary: This is the first report comparing EULAR and national treatment recommendations for PsA patients across Europe, and the first this decade to compare ASAS-EULAR and national treatment recommendations in axSpA patients. An electronic survey was completed from October 2021–April 2022 by rheumatologists in 15 European countries. One and four countries followed all EULAR and ASAS-EULAR recommendations, respectively. Five countries had no national treatment recommendations for PsA and/or axSpA, but followed other regulations. In several countries, national treatment recommendations predated the most recent EULAR/ASAS-EULAR recommendations. Entry criteria for starting biologic/targeted synthetic disease-modifying anti-rheumatic drugs varied considerably. In several countries, for PsA patients with significant skin involvement, interleukin-17 inhibitors were not given preference. The positioning of Janus Kinase inhibitors differed and Phosphodiesterase-4 inhibitors were not in use/reimbursed in most countries. This study may motivate European countries to update their national treatment recommendations, to align them better with the latest international recommendations.http://www.sciencedirect.com/science/article/pii/S2666776223001254Health policyPsoriatic arthritisAxial spondyloarthritisTreatment recommendations
spellingShingle Brigitte Michelsen
Mikkel Østergaard
Michael John Nissen
Adrian Ciurea
Burkhard Möller
Lykke Midtbøll Ørnbjerg
Jakub Zavada
Bente Glintborg
Alan MacDonald
Karin Laas
Dan Nordström
Bjorn Gudbjornsson
Florenzo Iannone
Pasoon Hellmand
Tore Kristian Kvien
Ana Maria Rodrigues
Catalin Codreanu
Ziga Rotar
Isabel Castrejón Fernández
Johan Karlsson Wallman
Jiri Vencovsky
Anne Gitte Loft
Maureen Heddle
Sigrid Vorobjov
Anna-Mari Hokkanen
Gerdur Gröndal
Marco Sebastiani
Marleen van de Sande
Eirik Klami Kristianslund
Maria José Santos
Corina Mogosan
Matija Tomsic
Federico Díaz-González
Daniela Di Giuseppe
Merete Lund Hetland
Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe
The Lancet Regional Health. Europe
Health policy
Psoriatic arthritis
Axial spondyloarthritis
Treatment recommendations
title Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe
title_full Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe
title_fullStr Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe
title_full_unstemmed Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe
title_short Differences and similarities between the EULAR/ASAS-EULAR and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across Europe
title_sort differences and similarities between the eular asas eular and national recommendations for treatment of patients with psoriatic arthritis and axial spondyloarthritis across europe
topic Health policy
Psoriatic arthritis
Axial spondyloarthritis
Treatment recommendations
url http://www.sciencedirect.com/science/article/pii/S2666776223001254
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