Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat
The purpose of the study was to compare the effectiveness of three anthelmintics against naturally occurring fascioliasis in goats as well as how they affected various hematological values over the course of 28 days. For this investigation, out of 417 goats, 60 were selected who were suffering from...
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| Format: | Article |
| Language: | English |
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Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv
2023-03-01
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| Series: | Ukrainian Journal of Veterinary and Agricultural Sciences |
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| Online Access: | https://ujvas.com.ua/index.php/journal/article/view/139 |
| _version_ | 1797772019904806912 |
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| author | Md. Ashraf Zaman Faruk |
| author_facet | Md. Ashraf Zaman Faruk |
| author_sort | Md. Ashraf Zaman Faruk |
| collection | DOAJ |
| description | The purpose of the study was to compare the effectiveness of three anthelmintics against naturally occurring fascioliasis in goats as well as how they affected various hematological values over the course of 28 days. For this investigation, out of 417 goats, 60 were selected who were suffering from liver fluke infection. After being randomly divided into four groups of 15 animals each, the first three groups got treatment with triclabendazole, oxyclozanide, and nitroxynil while the fourth group was kept as a control group and received no medication. The results of the study showed that the egg per gram (EPG) count of the treatment groups significantly decreased successively (P < 0.01) on days 3rd, 7th, 14th, and 28th, whereas the control group produced significantly from day 3rd through the experimental period. Results revealed that the mean EPG was reduced by 78.40 %, 73.33 %, and 83.11 %, respectively, following treatment with triclabendazole, oxyclozanide, and nitroxynil, while the mean EPG production was 22.66 % in the control group. Hematological parameters including Hb, PCV, and TEC values, were lower before the treatment but turned to increase significantly (P < 0.01) on study day 28th, however, the mean TLC values were decreased substantially (P < 0.01) compared to the untreated control group. This result may indicate that all three anthelmintics were efficient, but nitroxynil had a relatively higher efficacy against goat fascioliasis regarding on the EPG and hematological indices. |
| first_indexed | 2024-03-12T21:45:59Z |
| format | Article |
| id | doaj.art-1fc25801f0bf49de8f545347614c719f |
| institution | Directory Open Access Journal |
| issn | 2617-6149 |
| language | English |
| last_indexed | 2024-03-12T21:45:59Z |
| publishDate | 2023-03-01 |
| publisher | Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv |
| record_format | Article |
| series | Ukrainian Journal of Veterinary and Agricultural Sciences |
| spelling | doaj.art-1fc25801f0bf49de8f545347614c719f2023-07-26T11:58:44ZengStepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies LvivUkrainian Journal of Veterinary and Agricultural Sciences2617-61492023-03-01613910.32718/ujvas6-1.01139Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goatMd. Ashraf Zaman Faruk0Upazilla Livestock Office and Veterinary Hospital, Department of Livestock Services (DLS), Naldanga, Natore 6403, Bangla-desh Department of Anatomy and Histology, Bangladesh Agricultural University, Mymensingh 2202, BangladeshThe purpose of the study was to compare the effectiveness of three anthelmintics against naturally occurring fascioliasis in goats as well as how they affected various hematological values over the course of 28 days. For this investigation, out of 417 goats, 60 were selected who were suffering from liver fluke infection. After being randomly divided into four groups of 15 animals each, the first three groups got treatment with triclabendazole, oxyclozanide, and nitroxynil while the fourth group was kept as a control group and received no medication. The results of the study showed that the egg per gram (EPG) count of the treatment groups significantly decreased successively (P < 0.01) on days 3rd, 7th, 14th, and 28th, whereas the control group produced significantly from day 3rd through the experimental period. Results revealed that the mean EPG was reduced by 78.40 %, 73.33 %, and 83.11 %, respectively, following treatment with triclabendazole, oxyclozanide, and nitroxynil, while the mean EPG production was 22.66 % in the control group. Hematological parameters including Hb, PCV, and TEC values, were lower before the treatment but turned to increase significantly (P < 0.01) on study day 28th, however, the mean TLC values were decreased substantially (P < 0.01) compared to the untreated control group. This result may indicate that all three anthelmintics were efficient, but nitroxynil had a relatively higher efficacy against goat fascioliasis regarding on the EPG and hematological indices.https://ujvas.com.ua/index.php/journal/article/view/139fascioliasis; hematology; nitroxynil; oxyclozanide; triclabendazole |
| spellingShingle | Md. Ashraf Zaman Faruk Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat Ukrainian Journal of Veterinary and Agricultural Sciences fascioliasis; hematology; nitroxynil; oxyclozanide; triclabendazole |
| title | Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat |
| title_full | Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat |
| title_fullStr | Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat |
| title_full_unstemmed | Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat |
| title_short | Drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat |
| title_sort | drug potency effects of three anthelmintics against natural fascioliasis with hematological values in goat |
| topic | fascioliasis; hematology; nitroxynil; oxyclozanide; triclabendazole |
| url | https://ujvas.com.ua/index.php/journal/article/view/139 |
| work_keys_str_mv | AT mdashrafzamanfaruk drugpotencyeffectsofthreeanthelminticsagainstnaturalfascioliasiswithhematologicalvaluesingoat |