Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016
Abstract In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate subtype diversity, spatiotemporal distribution and genetic relationships between wi...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2019-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-019-50170-8 |
| _version_ | 1818993593407242240 |
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| author | Saskia A. Bergervoet Sylvia B. E. Pritz-Verschuren Jose L. Gonzales Alex Bossers Marjolein J. Poen Jayeeta Dutta Zenab Khan Divya Kriti Harm van Bakel Ruth Bouwstra Ron A. M. Fouchier Nancy Beerens |
| author_facet | Saskia A. Bergervoet Sylvia B. E. Pritz-Verschuren Jose L. Gonzales Alex Bossers Marjolein J. Poen Jayeeta Dutta Zenab Khan Divya Kriti Harm van Bakel Ruth Bouwstra Ron A. M. Fouchier Nancy Beerens |
| author_sort | Saskia A. Bergervoet |
| collection | DOAJ |
| description | Abstract In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate subtype diversity, spatiotemporal distribution and genetic relationships between wild bird and poultry viruses. We observed close species-dependent associations among hemagglutinin and neuraminidase subtypes. Not all subtypes detected in wild birds were found in poultry, suggesting transmission to poultry is selective and likely depends on viral factors that determine host range restriction. Subtypes commonly detected in poultry were in wild birds most frequently detected in mallards and geese. Different temporal patterns in virus prevalence were observed between wild bird species. Virus detections in domestic ducks coincided with the prevalence peak in wild ducks, whereas virus detections in other poultry types were made throughout the year. Genetic analysis of the surface genes demonstrated that most poultry viruses were related to locally circulating wild bird viruses, but no direct spatiotemporal link was observed. Results indicate prolonged undetected virus circulation and frequent reassortment events with local and newly introduced viruses within the wild bird population. Increased knowledge on LPAI virus circulation can be used to improve surveillance strategies. |
| first_indexed | 2024-12-20T20:44:31Z |
| format | Article |
| id | doaj.art-1fca82abd6cb4a66931ac41099bda507 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-20T20:44:31Z |
| publishDate | 2019-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-1fca82abd6cb4a66931ac41099bda5072022-12-21T19:27:04ZengNature PortfolioScientific Reports2045-23222019-09-019111210.1038/s41598-019-50170-8Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016Saskia A. Bergervoet0Sylvia B. E. Pritz-Verschuren1Jose L. Gonzales2Alex Bossers3Marjolein J. Poen4Jayeeta Dutta5Zenab Khan6Divya Kriti7Harm van Bakel8Ruth Bouwstra9Ron A. M. Fouchier10Nancy Beerens11Department of Virology, Wageningen Bioveterinary ResearchDepartment of Virology, Wageningen Bioveterinary ResearchDepartment of Epidemiology, Wageningen Bioveterinary ResearchDepartment of Infection Biology, Wageningen Bioveterinary ResearchDepartment of Viroscience, Erasmus MCDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount SinaiDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount SinaiDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount SinaiDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount SinaiGD Animal Health ServiceDepartment of Viroscience, Erasmus MCDepartment of Virology, Wageningen Bioveterinary ResearchAbstract In this study, we explore the circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands. Surveillance data collected between 2006 and 2016 was used to evaluate subtype diversity, spatiotemporal distribution and genetic relationships between wild bird and poultry viruses. We observed close species-dependent associations among hemagglutinin and neuraminidase subtypes. Not all subtypes detected in wild birds were found in poultry, suggesting transmission to poultry is selective and likely depends on viral factors that determine host range restriction. Subtypes commonly detected in poultry were in wild birds most frequently detected in mallards and geese. Different temporal patterns in virus prevalence were observed between wild bird species. Virus detections in domestic ducks coincided with the prevalence peak in wild ducks, whereas virus detections in other poultry types were made throughout the year. Genetic analysis of the surface genes demonstrated that most poultry viruses were related to locally circulating wild bird viruses, but no direct spatiotemporal link was observed. Results indicate prolonged undetected virus circulation and frequent reassortment events with local and newly introduced viruses within the wild bird population. Increased knowledge on LPAI virus circulation can be used to improve surveillance strategies.https://doi.org/10.1038/s41598-019-50170-8 |
| spellingShingle | Saskia A. Bergervoet Sylvia B. E. Pritz-Verschuren Jose L. Gonzales Alex Bossers Marjolein J. Poen Jayeeta Dutta Zenab Khan Divya Kriti Harm van Bakel Ruth Bouwstra Ron A. M. Fouchier Nancy Beerens Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016 Scientific Reports |
| title | Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016 |
| title_full | Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016 |
| title_fullStr | Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016 |
| title_full_unstemmed | Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016 |
| title_short | Circulation of low pathogenic avian influenza (LPAI) viruses in wild birds and poultry in the Netherlands, 2006–2016 |
| title_sort | circulation of low pathogenic avian influenza lpai viruses in wild birds and poultry in the netherlands 2006 2016 |
| url | https://doi.org/10.1038/s41598-019-50170-8 |
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