Liver Kinase B1 Regulates Remodeling of the Tumor Microenvironment in Triple-Negative Breast Cancer
Liver kinase B1 (LKB1) is a potent tumor suppressor that regulates cellular energy balance and metabolism as an upstream kinase of the AMP-activated protein kinase (AMPK) pathway. LKB1 regulates cancer cell invasion and metastasis in multiple cancer types, including breast cancer. In this study, we...
Main Authors: | Connor T. King, Margarite D. Matossian, Jonathan J. Savoie, Khoa Nguyen, Maryl K. Wright, C. Ethan Byrne, Steven Elliott, Hope E. Burks, Melyssa R. Bratton, Nicholas C. Pashos, Bruce A. Bunnell, Matthew E. Burow, Bridgette M. Collins-Burow, Elizabeth C. Martin |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-06-01
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Series: | Frontiers in Molecular Biosciences |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmolb.2022.847505/full |
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