MicroRNA-325-3p Facilitates Immune Escape of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling

MicroRNA-325-3p Facilitates Immune Escape of <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> through Targeting LNX1 via NEK6 Accumulation to Promote Anti-Apoptotic STAT3 Signaling

ABSTRACT Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis that poses threats to the public. M. tuberculosis survives in macrophages by escaping from immune surveillance and clearance, which exacerbates the bacterial proliferation. However, the molecular mechanisms of t...

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Bibliographic Details
Main Authors: Beibei Fu, Weiwei Xue, Haiwei Zhang, Rui Zhang, Kelly Feldman, Qingting Zhao, Shanfu Zhang, Lei Shi, Krishna Chaitanya Pavani, Weiqi Nian, Xiaoyuan Lin, Haibo Wu
Format: Article
Language:English
Published: American Society for Microbiology 2020-06-01
Series:mBio
Subjects:
Mycobacterium tuberculosis
microRNA
macrophage
ubiquitination
immune escape
Online Access:https://journals.asm.org/doi/10.1128/mBio.00557-20

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