Identifying Potent Fat Mass and Obesity-Associated Protein Inhibitors Using Deep Learning-Based Hybrid Procedures

Identifying Potent Fat Mass and Obesity-Associated Protein Inhibitors Using Deep Learning-Based Hybrid Procedures

The fat mass and obesity-associated (FTO) protein catalyzes metal-dependent modifications of nucleic acids, namely the demethylation of methyl adenosine inside mRNA molecules. The FTO protein has been identified as a potential target for developing anticancer therapies. Identifying a suitable ligand...

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Bibliographic Details
Main Authors: Kannan Mayuri, Durairaj Varalakshmi, Mayakrishnan Tharaheswari, Chaitanya Sree Somala, Selvaraj Sathya Priya, Nagaraj Bharathkumar, Renganathan Senthil, Raja Babu Singh Kushwah, Sundaram Vickram, Thirunavukarasou Anand, Konda Mani Saravanan
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:BioMedInformatics
Subjects:
FTO protein
deep learning-based screening
molecular docking
molecular simulations
drug screening
Online Access:https://www.mdpi.com/2673-7426/4/1/20

Internet

https://www.mdpi.com/2673-7426/4/1/20

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