Health-related quality of life in postrenal transplant patients: A single-center study
Background: The study was conducted to look for association of health-related quality of life (HRQoL) with renal functions in renal transplant recipients and to examine which clinical measures after renal transplantation are connected to aspects of their HRQoL. Materials and Methods: The study was c...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-01-01
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| Series: | Indian Journal of Transplantation |
| Subjects: | |
| Online Access: | http://www.ijtonline.in/article.asp?issn=2212-0017;year=2018;volume=12;issue=1;spage=35;epage=40;aulast=Gautam |
| _version_ | 1818937220071948288 |
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| author | Rajesh Gautam Manish Ramesh Balwani Vivek B Kute Umesh Godhani Praveen Ghule Pankaj Shah Manoj Gumber Hargovind L Trivedi |
| author_facet | Rajesh Gautam Manish Ramesh Balwani Vivek B Kute Umesh Godhani Praveen Ghule Pankaj Shah Manoj Gumber Hargovind L Trivedi |
| author_sort | Rajesh Gautam |
| collection | DOAJ |
| description | Background: The study was conducted to look for association of health-related quality of life (HRQoL) with renal functions in renal transplant recipients and to examine which clinical measures after renal transplantation are connected to aspects of their HRQoL. Materials and Methods: The study was carried out at IKDRC/ITS, Ahmedabad, between 2013 and 2016. Only patients who completed minimum 3 months posttransplant were included in the study. The responses were summarized and transformed to give eight summary scales which were grouped as physical component summary (PCS) and mental component summary (MCS) to give total HRQoL. Results: Out of 54 patients, 74% were males and 26% patients were females. Age distribution was between 18 and 62 years. Most common cause of end-stage renal disease was chronic glomerulonephritis (42.6%). Forty-seven patients underwent live-related kidney transplant while 7 received kidneys from cadaver. Mental health and MCS scores in males were significantly higher (<0.05) than females. With respect to age, the transplant patients were divided into four groups: younger than 30 years, 30–39 years, 40–49 years, and 50-year-old or older. No difference was found in any scale score between the age groups. The scale scores of PCS in patients with serum creatinine level >2 mg/dL were significantly lower (<0.05) than those of patients with serum creatinine <2 mg/dl. When compared in between patients who had rejection to those who did not, there was no significant difference in MCS and PCS. The scores of patients with cadaveric transplantation were similar to those who received a living-related transplantation. Longer time since the transplant operation was significantly associated with lower scores of the vitality scale. Conclusion: SF-36 V2 is a good tool to monitor HRQoL in renal transplant recipients. Episodes of hospitalization and rejection did not affect the present HRQoL in our study. |
| first_indexed | 2024-12-20T05:48:29Z |
| format | Article |
| id | doaj.art-1fd0c6c3c58b472482e9ff3ce4693ebd |
| institution | Directory Open Access Journal |
| issn | 2212-0017 2212-0025 |
| language | English |
| last_indexed | 2024-12-20T05:48:29Z |
| publishDate | 2018-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Transplantation |
| spelling | doaj.art-1fd0c6c3c58b472482e9ff3ce4693ebd2022-12-21T19:51:14ZengWolters Kluwer Medknow PublicationsIndian Journal of Transplantation2212-00172212-00252018-01-01121354010.4103/ijot.ijot_61_17Health-related quality of life in postrenal transplant patients: A single-center studyRajesh GautamManish Ramesh BalwaniVivek B KuteUmesh GodhaniPraveen GhulePankaj ShahManoj GumberHargovind L TrivediBackground: The study was conducted to look for association of health-related quality of life (HRQoL) with renal functions in renal transplant recipients and to examine which clinical measures after renal transplantation are connected to aspects of their HRQoL. Materials and Methods: The study was carried out at IKDRC/ITS, Ahmedabad, between 2013 and 2016. Only patients who completed minimum 3 months posttransplant were included in the study. The responses were summarized and transformed to give eight summary scales which were grouped as physical component summary (PCS) and mental component summary (MCS) to give total HRQoL. Results: Out of 54 patients, 74% were males and 26% patients were females. Age distribution was between 18 and 62 years. Most common cause of end-stage renal disease was chronic glomerulonephritis (42.6%). Forty-seven patients underwent live-related kidney transplant while 7 received kidneys from cadaver. Mental health and MCS scores in males were significantly higher (<0.05) than females. With respect to age, the transplant patients were divided into four groups: younger than 30 years, 30–39 years, 40–49 years, and 50-year-old or older. No difference was found in any scale score between the age groups. The scale scores of PCS in patients with serum creatinine level >2 mg/dL were significantly lower (<0.05) than those of patients with serum creatinine <2 mg/dl. When compared in between patients who had rejection to those who did not, there was no significant difference in MCS and PCS. The scores of patients with cadaveric transplantation were similar to those who received a living-related transplantation. Longer time since the transplant operation was significantly associated with lower scores of the vitality scale. Conclusion: SF-36 V2 is a good tool to monitor HRQoL in renal transplant recipients. Episodes of hospitalization and rejection did not affect the present HRQoL in our study.http://www.ijtonline.in/article.asp?issn=2212-0017;year=2018;volume=12;issue=1;spage=35;epage=40;aulast=GautamHealth-related quality of lifemental component scalephysical component scalerenal transplantation |
| spellingShingle | Rajesh Gautam Manish Ramesh Balwani Vivek B Kute Umesh Godhani Praveen Ghule Pankaj Shah Manoj Gumber Hargovind L Trivedi Health-related quality of life in postrenal transplant patients: A single-center study Indian Journal of Transplantation Health-related quality of life mental component scale physical component scale renal transplantation |
| title | Health-related quality of life in postrenal transplant patients: A single-center study |
| title_full | Health-related quality of life in postrenal transplant patients: A single-center study |
| title_fullStr | Health-related quality of life in postrenal transplant patients: A single-center study |
| title_full_unstemmed | Health-related quality of life in postrenal transplant patients: A single-center study |
| title_short | Health-related quality of life in postrenal transplant patients: A single-center study |
| title_sort | health related quality of life in postrenal transplant patients a single center study |
| topic | Health-related quality of life mental component scale physical component scale renal transplantation |
| url | http://www.ijtonline.in/article.asp?issn=2212-0017;year=2018;volume=12;issue=1;spage=35;epage=40;aulast=Gautam |
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