EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS
Objective: to evaluate the efficiency of antiviral therapy in patients with herpetic infection-complicated rheumatoid arthritis (RA) who receive the basic therapy. Subjects and methods. One hundred and thirty patients with recurrent herpesvirus infection were enrolled in the prospective comparative...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IMA-PRESS LLC
2009-06-01
|
| Series: | Современная ревматология |
| Subjects: | |
| Online Access: | https://mrj.ima-press.net/mrj/article/view/224 |
| _version_ | 1797876880233201664 |
|---|---|
| author | O N Egorova R M Balabanova N E Lopatina A K Kaptayeva T P Fedina E G Sazhina E L Nasonov G N Chuvirov |
| author_facet | O N Egorova R M Balabanova N E Lopatina A K Kaptayeva T P Fedina E G Sazhina E L Nasonov G N Chuvirov |
| author_sort | O N Egorova |
| collection | DOAJ |
| description | Objective: to evaluate the efficiency of antiviral therapy in patients with herpetic infection-complicated rheumatoid arthritis (RA) who receive the basic therapy. Subjects and methods. One hundred and thirty patients with recurrent herpesvirus infection were enrolled in the prospective comparative study. The patients were divided into 3 groups: 1) in addition to the basic therapy, the patients received Panavir®; 2) those who took Acyclovir; and 3) those who had the basic therapy alone. In 90 of the 130 examinees, high titers of antiviral IgG antibodies to cytomegalovirus and Epstein-Barr virus were found in 60 and 48,8%, respectively. The interferon-deficiency syndrome was diagnosed in 72 (80,0%) patients. Results. Virostatic therapy may be recommended for patients with RA concurrent with recurrent herpesvirus infection. |
| first_indexed | 2024-04-10T02:08:26Z |
| format | Article |
| id | doaj.art-1fd39260a2e04881858b68489e728be5 |
| institution | Directory Open Access Journal |
| issn | 1996-7012 2310-158X |
| language | Russian |
| last_indexed | 2024-04-10T02:08:26Z |
| publishDate | 2009-06-01 |
| publisher | IMA-PRESS LLC |
| record_format | Article |
| series | Современная ревматология |
| spelling | doaj.art-1fd39260a2e04881858b68489e728be52023-03-13T08:39:20ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2009-06-0132424710.14412/1996-7012-2009-5391529EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITISO N EgorovaR M BalabanovaN E LopatinaA K KaptayevaT P FedinaE G SazhinaE L NasonovG N ChuvirovObjective: to evaluate the efficiency of antiviral therapy in patients with herpetic infection-complicated rheumatoid arthritis (RA) who receive the basic therapy. Subjects and methods. One hundred and thirty patients with recurrent herpesvirus infection were enrolled in the prospective comparative study. The patients were divided into 3 groups: 1) in addition to the basic therapy, the patients received Panavir®; 2) those who took Acyclovir; and 3) those who had the basic therapy alone. In 90 of the 130 examinees, high titers of antiviral IgG antibodies to cytomegalovirus and Epstein-Barr virus were found in 60 and 48,8%, respectively. The interferon-deficiency syndrome was diagnosed in 72 (80,0%) patients. Results. Virostatic therapy may be recommended for patients with RA concurrent with recurrent herpesvirus infection.https://mrj.ima-press.net/mrj/article/view/224ревматоидный артритгерпесвирусыпанавир®ацикловир |
| spellingShingle | O N Egorova R M Balabanova N E Lopatina A K Kaptayeva T P Fedina E G Sazhina E L Nasonov G N Chuvirov EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS Современная ревматология ревматоидный артрит герпесвирусы панавир® ацикловир |
| title | EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS |
| title_full | EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS |
| title_fullStr | EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS |
| title_full_unstemmed | EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS |
| title_short | EFFICACY OF PANAVIR® AND ACYCLOVIR IN THE COMPLEX THERAPY OF HERPETIC INFECTION-COMPLICATED RHEUMATOID ARTHRITIS |
| title_sort | efficacy of panavir r and acyclovir in the complex therapy of herpetic infection complicated rheumatoid arthritis |
| topic | ревматоидный артрит герпесвирусы панавир® ацикловир |
| url | https://mrj.ima-press.net/mrj/article/view/224 |
| work_keys_str_mv | AT onegorova efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT rmbalabanova efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT nelopatina efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT akkaptayeva efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT tpfedina efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT egsazhina efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT elnasonov efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis AT gnchuvirov efficacyofpanavirandacyclovirinthecomplextherapyofherpeticinfectioncomplicatedrheumatoidarthritis |