Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome

Protein nanoparticle-induced osmotic pressure gradients modify pulmonary edema through hyperpermeability in acute respiratory distress syndrome

Abstract Acute respiratory distress syndrome (ARDS), caused by noncardiogenic pulmonary edema (PE), contributes significantly to Coronavirus 2019 (COVID-19)-associated morbidity and mortality. We explored the effect of transmembrane osmotic pressure (OP) gradients in PE using a fluorescence resonanc...

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Bibliographic Details
Main Authors: ZhiZhi Qian, QianYi Wang, ZhaoShun Qiu, DanYang Li, ChenCheng Zhang, XiYu Xiong, ZiHui Zheng, QinLi Ruan, YiChen Guo, Jun Guo
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Nanobiotechnology
Subjects:
ARDS
Pulmonary edema
Protein nanoparticle-induced osmotic pressure
Voltage-dependent ion channels
Multi-targeted blockade
Online Access:https://doi.org/10.1186/s12951-022-01519-1

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