BP-M345, a New Diarylpentanoid with Promising Antimitotic Activity
Previously, we reported the in vitro growth inhibitory effect of diarylpentanoid BP-M345 on human cancer cells. Nevertheless, at that time, the cellular mechanism through which BP-M345 exerts its growth inhibitory effect remained to be explored. In the present work, we report its mechanism of action...
Main Authors: | Pedro Novais, Patrícia M. A. Silva, Joana Moreira, Andreia Palmeira, Isabel Amorim, Madalena Pinto, Honorina Cidade, Hassan Bousbaa |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-11-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/23/7139 |
Similar Items
-
BP-M345 as a Basis for the Discovery of New Diarylpentanoids with Promising Antimitotic Activity
by: Joana Moreira, et al.
Published: (2024-01-01) -
Structure–Activity Relationship Studies of Chalcones and Diarylpentanoids with Antitumor Activity: Potency and Selectivity Optimization
by: Joana Moreira, et al.
Published: (2023-09-01) -
Discovery of a New Chalcone-Trimethoxycinnamide Hybrid with Antimitotic Effect: Design, Synthesis, and Structure—Activity Relationship Studies
by: Joana Moreira, et al.
Published: (2023-06-01) -
Bioactive Diarylpentanoids: Insights into the Biological Effects beyond Antitumor Activity and Structure–Activity Relationships
by: Joana Moreira, et al.
Published: (2022-09-01) -
A Pyranoxanthone as a Potent Antimitotic and Sensitizer of Cancer Cells to Low Doses of Paclitaxel
by: Fábio França, et al.
Published: (2020-12-01)