The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis

The objective of this study was to evaluate the quality of life in patients with ulcerative colitis (UC) of moderate severity and concomitant subclinical atherosclerosis before and after combination treatment with statin and omega-3 polyunsaturated fatty acids (PUFAs). In patients with UC and concom...

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Main Authors: I.V. Chopei, T.M. Ternushchak, S.S. Filip
Format: Article
Language:English
Published: Zaslavsky O.Yu. 2015-04-01
Series:Gastroenterologìa
Subjects:
Online Access:http://gastro.zaslavsky.com.ua/article/view/81500
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author I.V. Chopei
T.M. Ternushchak
S.S. Filip
author_facet I.V. Chopei
T.M. Ternushchak
S.S. Filip
author_sort I.V. Chopei
collection DOAJ
description The objective of this study was to evaluate the quality of life in patients with ulcerative colitis (UC) of moderate severity and concomitant subclinical atherosclerosis before and after combination treatment with statin and omega-3 polyunsaturated fatty acids (PUFAs). In patients with UC and concomitant atherosclerosis we have detected deterioration in quality of life mostly by the components of physical health (SF-36 questionnaire), which is directly proportional to the degree of atherosclerosis severity (p < 0.05). During combined treatment with statins and omega-3 PUFAs, there was a significant improvement in parameters of not only physical, but also mental health (p < 0.05). Analyzing data by specialized GSRS questionnaires, we have noted improvement in quality of life by three of the five scales — abdominal pain, dyspeptic and diarrheal syndromes (p < 0.05).
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spelling doaj.art-1fdb2d7e1d634e6496433d1ff4827b392022-12-22T04:10:26ZengZaslavsky O.Yu.Gastroenterologìa2308-20972518-78802015-04-01492.56677210.22141/2308-2097.2.56.2015.8150081500The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical AtherosclerosisI.V. Chopei0T.M. Ternushchak1S.S. Filip2Institute of Postgraduate Education and Preuniversity Training of Higher State Educational Institution «Uzhhorod National University»Institute of Postgraduate Education and Preuniversity Training of Higher State Educational Institution «Uzhhorod National University»Medical Faculty of Higher State Educational Institution «Uzhhorod National University», UzhhorodThe objective of this study was to evaluate the quality of life in patients with ulcerative colitis (UC) of moderate severity and concomitant subclinical atherosclerosis before and after combination treatment with statin and omega-3 polyunsaturated fatty acids (PUFAs). In patients with UC and concomitant atherosclerosis we have detected deterioration in quality of life mostly by the components of physical health (SF-36 questionnaire), which is directly proportional to the degree of atherosclerosis severity (p < 0.05). During combined treatment with statins and omega-3 PUFAs, there was a significant improvement in parameters of not only physical, but also mental health (p < 0.05). Analyzing data by specialized GSRS questionnaires, we have noted improvement in quality of life by three of the five scales — abdominal pain, dyspeptic and diarrheal syndromes (p < 0.05).http://gastro.zaslavsky.com.ua/article/view/81500ulcerative colitissubclinical atherosclerosisquality of lifestatinsomega-3 polyunsaturated fatty acids
spellingShingle I.V. Chopei
T.M. Ternushchak
S.S. Filip
The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis
Gastroenterologìa
ulcerative colitis
subclinical atherosclerosis
quality of life
statins
omega-3 polyunsaturated fatty acids
title The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis
title_full The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis
title_fullStr The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis
title_full_unstemmed The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis
title_short The Quality of Life in Patients with Ulcerative Colitis and Concomitant Subclinical Atherosclerosis
title_sort quality of life in patients with ulcerative colitis and concomitant subclinical atherosclerosis
topic ulcerative colitis
subclinical atherosclerosis
quality of life
statins
omega-3 polyunsaturated fatty acids
url http://gastro.zaslavsky.com.ua/article/view/81500
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