Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis
ObjectiveTo comprehensively evaluate the efficacy of non-invasive brain stimulation (NIBS) in patients with autism spectrum disorder (ASD) in randomized controlled trials (RCT), providing a reference for future research on the same topic.MethodsFive databases were searched (Pubmed, Web of Science, M...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-06-01
|
| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1147327/full |
| _version_ | 1797792575634014208 |
|---|---|
| author | Annan Liu Chao Gong Bobo Wang Jiaxing Sun Zhimei Jiang |
| author_facet | Annan Liu Chao Gong Bobo Wang Jiaxing Sun Zhimei Jiang |
| author_sort | Annan Liu |
| collection | DOAJ |
| description | ObjectiveTo comprehensively evaluate the efficacy of non-invasive brain stimulation (NIBS) in patients with autism spectrum disorder (ASD) in randomized controlled trials (RCT), providing a reference for future research on the same topic.MethodsFive databases were searched (Pubmed, Web of Science, Medline, Embase, and Cochrane library) and tracked relevant references, Meta-analysis was performed using RevMan 5.3 software.ResultsTwenty-two references (829 participants) were included. The results of the meta-analysis showed that NIBS had positive effects on repetitive and stereotypical behaviors, cognitive function, and executive function in autistic patients. Most of the included studies had a moderate to high risk of bias, Mainly because of the lack of blinding of subjects and assessors to treatment assignment, as well as the lack of continuous observation of treatment effects.ConclusionAvailable evidence supports an improvement in some aspects of NIBS in patients with ASD. However, due to the quality of the original studies and significant publication bias, this evidence must be treated with caution. Further large multicenter randomized double-blind controlled trials and appropriate follow-up observations are needed to further evaluate the specific efficacy of NIBS in patients with ASD. |
| first_indexed | 2024-03-13T02:35:00Z |
| format | Article |
| id | doaj.art-1fdd2a1163814ae1bae837677c3943bc |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-03-13T02:35:00Z |
| publishDate | 2023-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-1fdd2a1163814ae1bae837677c3943bc2023-06-29T05:34:42ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402023-06-011410.3389/fpsyt.2023.11473271147327Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysisAnnan Liu0Chao Gong1Bobo Wang2Jiaxing Sun3Zhimei Jiang4Jiamusi University Affiliated No.3 Hospital, Jiamusi, ChinaJiamusi Medical College, Jiamusi, Heilongjiang, ChinaJiamusi Medical College, Jiamusi, Heilongjiang, ChinaJiamusi Medical College, Jiamusi, Heilongjiang, ChinaJiamusi University College of Rehabilitation Medicine, Jiamusi, Heilongjiang, ChinaObjectiveTo comprehensively evaluate the efficacy of non-invasive brain stimulation (NIBS) in patients with autism spectrum disorder (ASD) in randomized controlled trials (RCT), providing a reference for future research on the same topic.MethodsFive databases were searched (Pubmed, Web of Science, Medline, Embase, and Cochrane library) and tracked relevant references, Meta-analysis was performed using RevMan 5.3 software.ResultsTwenty-two references (829 participants) were included. The results of the meta-analysis showed that NIBS had positive effects on repetitive and stereotypical behaviors, cognitive function, and executive function in autistic patients. Most of the included studies had a moderate to high risk of bias, Mainly because of the lack of blinding of subjects and assessors to treatment assignment, as well as the lack of continuous observation of treatment effects.ConclusionAvailable evidence supports an improvement in some aspects of NIBS in patients with ASD. However, due to the quality of the original studies and significant publication bias, this evidence must be treated with caution. Further large multicenter randomized double-blind controlled trials and appropriate follow-up observations are needed to further evaluate the specific efficacy of NIBS in patients with ASD.https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1147327/fullautismnon-invasive neurostimulationtranscranial direct current stimulationtranscranial magnetic stimulationmeta-analysis |
| spellingShingle | Annan Liu Chao Gong Bobo Wang Jiaxing Sun Zhimei Jiang Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis Frontiers in Psychiatry autism non-invasive neurostimulation transcranial direct current stimulation transcranial magnetic stimulation meta-analysis |
| title | Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis |
| title_full | Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis |
| title_fullStr | Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis |
| title_full_unstemmed | Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis |
| title_short | Non-invasive brain stimulation for patient with autism: a systematic review and meta-analysis |
| title_sort | non invasive brain stimulation for patient with autism a systematic review and meta analysis |
| topic | autism non-invasive neurostimulation transcranial direct current stimulation transcranial magnetic stimulation meta-analysis |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1147327/full |
| work_keys_str_mv | AT annanliu noninvasivebrainstimulationforpatientwithautismasystematicreviewandmetaanalysis AT chaogong noninvasivebrainstimulationforpatientwithautismasystematicreviewandmetaanalysis AT bobowang noninvasivebrainstimulationforpatientwithautismasystematicreviewandmetaanalysis AT jiaxingsun noninvasivebrainstimulationforpatientwithautismasystematicreviewandmetaanalysis AT zhimeijiang noninvasivebrainstimulationforpatientwithautismasystematicreviewandmetaanalysis |