PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger
This work reports the use of the Octave, a free computational software, to optimize the experimental design in the synthesis of ethyl oleate from oleic acid and ethanol catalyzed by a native lipase from Aspergillus niger. The central composite factorial design (CCD) was performed with 2 levels and 3...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2022-09-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000700782&tlng=pt |
| _version_ | 1818016434859540480 |
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| author | Sofia S. Dias Michele R. G. Dias Renata Danielle Adati Patrícia de O. Carvalho Cristiane Pilissão |
| author_facet | Sofia S. Dias Michele R. G. Dias Renata Danielle Adati Patrícia de O. Carvalho Cristiane Pilissão |
| author_sort | Sofia S. Dias |
| collection | DOAJ |
| description | This work reports the use of the Octave, a free computational software, to optimize the experimental design in the synthesis of ethyl oleate from oleic acid and ethanol catalyzed by a native lipase from Aspergillus niger. The central composite factorial design (CCD) was performed with 2 levels and 3 variables (temperature, mass of native A. niger lipase and oleic acid:ethanol molar ratio) in conjunction with response surface methodology (RSM). The results indicate that variable 1 (oleic acid:ethanol molar ratio; X1) and 2 (mass of A. niger lipase, X2), as well as the interaction between them, are statistically significant. The optimal reaction condition was estimated using ANOVA data and the response surface. The experimental results are consistent with those estimated, and thus, ethyl oleate was obtained with conversion (> 90%) using oleic acid and ethanol in a 1:2 molar ratio, A. niger lipase (8,00 mg) and temperature of 45 °C in 6 hours of reaction. |
| first_indexed | 2024-04-14T07:12:14Z |
| format | Article |
| id | doaj.art-1fdd3d34ecf3418abf727a681385bee1 |
| institution | Directory Open Access Journal |
| issn | 1678-7064 |
| language | English |
| last_indexed | 2024-04-14T07:12:14Z |
| publishDate | 2022-09-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-1fdd3d34ecf3418abf727a681385bee12022-12-22T02:06:23ZengSociedade Brasileira de QuímicaQuímica Nova1678-70642022-09-0145778278710.21577/0100-4042.20170879PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus nigerSofia S. DiasMichele R. G. DiasRenata Danielle AdatiPatrícia de O. CarvalhoCristiane Pilissãohttps://orcid.org/0000-0002-5410-3481This work reports the use of the Octave, a free computational software, to optimize the experimental design in the synthesis of ethyl oleate from oleic acid and ethanol catalyzed by a native lipase from Aspergillus niger. The central composite factorial design (CCD) was performed with 2 levels and 3 variables (temperature, mass of native A. niger lipase and oleic acid:ethanol molar ratio) in conjunction with response surface methodology (RSM). The results indicate that variable 1 (oleic acid:ethanol molar ratio; X1) and 2 (mass of A. niger lipase, X2), as well as the interaction between them, are statistically significant. The optimal reaction condition was estimated using ANOVA data and the response surface. The experimental results are consistent with those estimated, and thus, ethyl oleate was obtained with conversion (> 90%) using oleic acid and ethanol in a 1:2 molar ratio, A. niger lipase (8,00 mg) and temperature of 45 °C in 6 hours of reaction.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000700782&tlng=ptlipaseesterificationoleic acidStatisticOctave. |
| spellingShingle | Sofia S. Dias Michele R. G. Dias Renata Danielle Adati Patrícia de O. Carvalho Cristiane Pilissão PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger Química Nova lipase esterification oleic acid Statistic Octave. |
| title | PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger |
| title_full | PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger |
| title_fullStr | PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger |
| title_full_unstemmed | PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger |
| title_short | PLANEJAMENTO FATORIAL NA SÍNTESE DO OLEATO DE ETILA CATALISADA PELA LIPASE NATIVA DE Aspergillus niger |
| title_sort | planejamento fatorial na sintese do oleato de etila catalisada pela lipase nativa de aspergillus niger |
| topic | lipase esterification oleic acid Statistic Octave. |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000700782&tlng=pt |
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