Innovative Device for Indocianyne Green Navigational Surgery
Dynamic reality has been integrated into developing surgical techniques, with the goals of providing increased intraoperative accuracy, easier detection of critical anatomical landmarks, and better general results for the patient. Enhancement of the reality in surgical theaters using single or multi...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Ion Motofei, Carol Davila University
2020-04-01
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| Series: | Journal of Mind and Medical Sciences |
| Subjects: | |
| Online Access: | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1221&context=jmms |
| _version_ | 1811221865429991424 |
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| author | Cătălin Aliuș Nicolae Bacalbașa Cristian Bălălău |
| author_facet | Cătălin Aliuș Nicolae Bacalbașa Cristian Bălălău |
| author_sort | Cătălin Aliuș |
| collection | DOAJ |
| description | Dynamic reality has been integrated into developing surgical techniques, with the goals of providing increased intraoperative accuracy, easier detection of critical anatomical landmarks, and better general results for the patient. Enhancement of the reality in surgical theaters using single or multi sensorial augmenters (haptic, thermic and visual) has been reported with various degrees of success. This paper presents a novel device for navigational surgery and ancillary clinical applications based on the fluorescent properties of Indocyanine Green (ICG), a safe, FDA-approved dye that emits fluorescence at higher wavelengths than endogenous proteins. The latest technological developments and the aforementioned convenient quantum behavior of ICG allow for its effective identification in tissues by means of a complementary metal-oxide semiconductor (CMOS) infrared camera. Following fundamental research on the fluorophor in different biological suspensions and at various concentrations, our team has built a device that casts a beam of excitation light at 780nm and collects emission light at 810-830nm, filtering ambient light and endogenous autofluorescence. The emission light is fluorescent and infrared, unlike visible light. It can penetrate tissues up to 1.6cm in depth, providing after digitization into conventional imaging anatomical and functional data of immense intra-operative value. |
| first_indexed | 2024-04-12T08:07:33Z |
| format | Article |
| id | doaj.art-1fdd77dda52d49568c6d3a99bf931914 |
| institution | Directory Open Access Journal |
| issn | 2392-7674 2392-7674 |
| language | English |
| last_indexed | 2024-04-12T08:07:33Z |
| publishDate | 2020-04-01 |
| publisher | Ion Motofei, Carol Davila University |
| record_format | Article |
| series | Journal of Mind and Medical Sciences |
| spelling | doaj.art-1fdd77dda52d49568c6d3a99bf9319142022-12-22T03:41:05ZengIon Motofei, Carol Davila UniversityJournal of Mind and Medical Sciences2392-76742392-76742020-04-0171404510.22543/7674.71.P4045Innovative Device for Indocianyne Green Navigational SurgeryCătălin Aliuș0Nicolae Bacalbașa1Cristian Bălălău2UNIVERSITARY EMERGENCY CLINICAL HOSPITAL, BUCHAREST, ROMANIA CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY, BUCHAREST, ROMANIA Dynamic reality has been integrated into developing surgical techniques, with the goals of providing increased intraoperative accuracy, easier detection of critical anatomical landmarks, and better general results for the patient. Enhancement of the reality in surgical theaters using single or multi sensorial augmenters (haptic, thermic and visual) has been reported with various degrees of success. This paper presents a novel device for navigational surgery and ancillary clinical applications based on the fluorescent properties of Indocyanine Green (ICG), a safe, FDA-approved dye that emits fluorescence at higher wavelengths than endogenous proteins. The latest technological developments and the aforementioned convenient quantum behavior of ICG allow for its effective identification in tissues by means of a complementary metal-oxide semiconductor (CMOS) infrared camera. Following fundamental research on the fluorophor in different biological suspensions and at various concentrations, our team has built a device that casts a beam of excitation light at 780nm and collects emission light at 810-830nm, filtering ambient light and endogenous autofluorescence. The emission light is fluorescent and infrared, unlike visible light. It can penetrate tissues up to 1.6cm in depth, providing after digitization into conventional imaging anatomical and functional data of immense intra-operative value.https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1221&context=jmmsindocyanine greenlaparoscopic surgeryfluorescence |
| spellingShingle | Cătălin Aliuș Nicolae Bacalbașa Cristian Bălălău Innovative Device for Indocianyne Green Navigational Surgery Journal of Mind and Medical Sciences indocyanine green laparoscopic surgery fluorescence |
| title | Innovative Device for Indocianyne Green Navigational Surgery |
| title_full | Innovative Device for Indocianyne Green Navigational Surgery |
| title_fullStr | Innovative Device for Indocianyne Green Navigational Surgery |
| title_full_unstemmed | Innovative Device for Indocianyne Green Navigational Surgery |
| title_short | Innovative Device for Indocianyne Green Navigational Surgery |
| title_sort | innovative device for indocianyne green navigational surgery |
| topic | indocyanine green laparoscopic surgery fluorescence |
| url | https://scholar.valpo.edu/cgi/viewcontent.cgi?article=1221&context=jmms |
| work_keys_str_mv | AT catalinalius innovativedeviceforindocianynegreennavigationalsurgery AT nicolaebacalbasa innovativedeviceforindocianynegreennavigationalsurgery AT cristianbalalau innovativedeviceforindocianynegreennavigationalsurgery |