The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions
BackgroundTo assess the frequency of major complications after thermal ablation of liver tumours and to determine risk factors for adverse events.MethodsA retrospective study was conducted between January 2015 and January 2021. A total of 2,084 thermal ablation sessions in 1,592 patients with primar...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2022-09-01
|
| Series: | Frontiers in Surgery |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1010043/full |
| _version_ | 1798033888688209920 |
|---|---|
| author | Qiannan Huang Mengya Pang Qingjing Zeng Xuqi He Rongqin Zheng Mian Ge Kai Li |
| author_facet | Qiannan Huang Mengya Pang Qingjing Zeng Xuqi He Rongqin Zheng Mian Ge Kai Li |
| author_sort | Qiannan Huang |
| collection | DOAJ |
| description | BackgroundTo assess the frequency of major complications after thermal ablation of liver tumours and to determine risk factors for adverse events.MethodsA retrospective study was conducted between January 2015 and January 2021. A total of 2,084 thermal ablation sessions in 1,592 patients with primary and metastatic liver tumours were evaluated. The frequency of major complications was evaluated according to the Society of Interventional Radiology Standards, and putative predictors of adverse events were analysed using simple and multivariate logistic regression.ResultsThermal ablation-related mortality was 0.1% (2/2,084), with an overall major complication rate of 5.6% (117/2,084). The most frequent major complication was symptomatic pleural effusion (2.9%, 60/2,084). Multivariate logistic regression analysis revealed that a total maximum diameter of lesions >3 cm, microwave ablation (MWA) and MWA combined with radiofrequency ablation, intrahepatic cholangiocarcinoma and postoperative systemic inflammatory response syndrome were independent prognostic factors for major complications.ConclusionsThermal ablation of liver tumours is a safe procedure with an acceptable incidence of major complications. The risk factors identified in this study will help to stratify high-risk patients. |
| first_indexed | 2024-04-11T20:36:47Z |
| format | Article |
| id | doaj.art-1fe38a7c3b464847b04f5c61ef230749 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-04-11T20:36:47Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-1fe38a7c3b464847b04f5c61ef2307492022-12-22T04:04:21ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2022-09-01910.3389/fsurg.2022.10100431010043The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessionsQiannan Huang0Mengya Pang1Qingjing Zeng2Xuqi He3Rongqin Zheng4Mian Ge5Kai Li6Department of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaDepartment of Ultrasound, Guangdong Key Laboratory of Liver Disease Research, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, ChinaBackgroundTo assess the frequency of major complications after thermal ablation of liver tumours and to determine risk factors for adverse events.MethodsA retrospective study was conducted between January 2015 and January 2021. A total of 2,084 thermal ablation sessions in 1,592 patients with primary and metastatic liver tumours were evaluated. The frequency of major complications was evaluated according to the Society of Interventional Radiology Standards, and putative predictors of adverse events were analysed using simple and multivariate logistic regression.ResultsThermal ablation-related mortality was 0.1% (2/2,084), with an overall major complication rate of 5.6% (117/2,084). The most frequent major complication was symptomatic pleural effusion (2.9%, 60/2,084). Multivariate logistic regression analysis revealed that a total maximum diameter of lesions >3 cm, microwave ablation (MWA) and MWA combined with radiofrequency ablation, intrahepatic cholangiocarcinoma and postoperative systemic inflammatory response syndrome were independent prognostic factors for major complications.ConclusionsThermal ablation of liver tumours is a safe procedure with an acceptable incidence of major complications. The risk factors identified in this study will help to stratify high-risk patients.https://www.frontiersin.org/articles/10.3389/fsurg.2022.1010043/fullthermal ablationliver tumoursmajor complicationsultrasoundrisk factors |
| spellingShingle | Qiannan Huang Mengya Pang Qingjing Zeng Xuqi He Rongqin Zheng Mian Ge Kai Li The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions Frontiers in Surgery thermal ablation liver tumours major complications ultrasound risk factors |
| title | The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions |
| title_full | The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions |
| title_fullStr | The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions |
| title_full_unstemmed | The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions |
| title_short | The frequency and risk factors of major complications after thermal ablation of liver tumours in 2,084 ablation sessions |
| title_sort | frequency and risk factors of major complications after thermal ablation of liver tumours in 2 084 ablation sessions |
| topic | thermal ablation liver tumours major complications ultrasound risk factors |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2022.1010043/full |
| work_keys_str_mv | AT qiannanhuang thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT mengyapang thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT qingjingzeng thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT xuqihe thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT rongqinzheng thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT miange thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT kaili thefrequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT qiannanhuang frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT mengyapang frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT qingjingzeng frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT xuqihe frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT rongqinzheng frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT miange frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions AT kaili frequencyandriskfactorsofmajorcomplicationsafterthermalablationoflivertumoursin2084ablationsessions |