Sodium Valproate-Induced Chromatin Remodeling

Sodium Valproate-Induced Chromatin Remodeling

Valproic acid/sodium valproate (VPA), a drug originally prescribed as an anticonvulsant, has been widely reported to act on epigenetic marks by inducing histone acetylation, affecting the DNA and histone methylation status, and altering the expression of transcription factors, thus leading to modula...

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Bibliographic Details
Main Author: Maria Luiza S. Mello
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
chromatin
sodium valproate
epigenetics
histones
DNA
image analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.645518/full

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