Development of Apremilast Nanoemulsion-Loaded Chitosan Gels: In Vitro Evaluations and Anti-Inflammatory and Wound Healing Studies on a Rat Model

Development of Apremilast Nanoemulsion-Loaded Chitosan Gels: In Vitro Evaluations and Anti-Inflammatory and Wound Healing Studies on a Rat Model

Apremilast (APL) has profound anti-inflammatory and wound healing activity, alongside other dermal care. This study aims to develop APL-loaded NEs (ANE1-ANE5) using eucalyptus oil (EO) as the oil and Tween-80 and transcutol-HP (THP) as a surfactant and co-surfactant, respectively. The prepared NEs w...

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Bibliographic Details
Main Authors: Mohammed Muqtader Ahmed, Md. Khalid Anwer, Farhat Fatima, Amer S. Alali, Mohd Abul Kalam, Ameeduzzafar Zafar, Sultan Alshehri, Mohammed M. Ghoneim
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Gels
Subjects:
apremilast
nanoemulsion
chitosan
gels
stability
anti-inflammatory
Online Access:https://www.mdpi.com/2310-2861/8/5/253

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