A high-throughput assay for screening natural products that boost NK cell-mediated killing of cancer cells

A high-throughput assay for screening natural products that boost NK cell-mediated killing of cancer cells

Context Natural killer (NK) cells can eliminate malignant cells and play a vital role in immunosurveillance. Administration of natural compounds represents a promising approach for antitumor immunotherapy, which may enhance the NK cell activity via multiple mechanisms. Objective Establishing approac...

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Bibliographic Details
Main Authors: Zihang Xu, Xiaowen Zhu, Lin Su, Chunpu Zou, Xiao Chen, Yifei Hou, Chenyuan Gong, Wanyi Ng, Zhongya Ni, Lixin Wang, Xuewei Yan, Yangzhuangzhuang Zhu, Xiaoning Jiao, Chao Yao, Shiguo Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
cytotoxicity
non-small cell lung cancer
20-deoxyingenol 3-angelate
ingenol 3-angelate
Online Access:http://dx.doi.org/10.1080/13880209.2020.1748661

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