Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review
Shuwen Han,1 Jianlan Gao,1 Qing Zhou,2 Shanshan Liu,3 Caixia Wen,3 Xi Yang4 1Department of Medical Oncology, Huzhou Central Hospital, 2Department of Critical Care Medicine, Huzhou Central Hospital, 3Medical College of Nursing, Huzhou University, 4Department of Intervention and Radiotherapy, Huzhou C...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2018-01-01
|
| Series: | Cancer Management and Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/role-of-intestinal-flora-in-colorectal-cancer-from-the-metabolite-pers-peer-reviewed-article-CMAR |
| _version_ | 1818355451400552448 |
|---|---|
| author | Han S Gao J Zhou Q Liu S Wen C Yang X |
| author_facet | Han S Gao J Zhou Q Liu S Wen C Yang X |
| author_sort | Han S |
| collection | DOAJ |
| description | Shuwen Han,1 Jianlan Gao,1 Qing Zhou,2 Shanshan Liu,3 Caixia Wen,3 Xi Yang4 1Department of Medical Oncology, Huzhou Central Hospital, 2Department of Critical Care Medicine, Huzhou Central Hospital, 3Medical College of Nursing, Huzhou University, 4Department of Intervention and Radiotherapy, Huzhou Central Hospital, Huzhou, Zhejiang Province, People’s Republic of China Abstract: Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature on floral metabolites in colorectal cancer from three metabolic perspectives – including carbohydrate, lipid, and amino acid metabolism – was analyzed. An association network regarding the role of intestinal flora from a metabolic perspective was constructed by analyzing the previous literature to provide direction and insight for further research on intestinal flora in colorectal cancer. Keywords: colorectal cancer, bacteria, microbiology, carbohydrate metabolism, lipid metabolism, amino acids, inflammation |
| first_indexed | 2024-12-13T19:41:32Z |
| format | Article |
| id | doaj.art-1fe8111771f54cd3b9c89a87e5a84e6b |
| institution | Directory Open Access Journal |
| issn | 1179-1322 |
| language | English |
| last_indexed | 2024-12-13T19:41:32Z |
| publishDate | 2018-01-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Cancer Management and Research |
| spelling | doaj.art-1fe8111771f54cd3b9c89a87e5a84e6b2022-12-21T23:33:41ZengDove Medical PressCancer Management and Research1179-13222018-01-01Volume 1019920636589Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic reviewHan SGao JZhou QLiu SWen CYang XShuwen Han,1 Jianlan Gao,1 Qing Zhou,2 Shanshan Liu,3 Caixia Wen,3 Xi Yang4 1Department of Medical Oncology, Huzhou Central Hospital, 2Department of Critical Care Medicine, Huzhou Central Hospital, 3Medical College of Nursing, Huzhou University, 4Department of Intervention and Radiotherapy, Huzhou Central Hospital, Huzhou, Zhejiang Province, People’s Republic of China Abstract: Colorectal cancer is one of the most common human malignant tumors. Recent research has shown that colorectal cancer is a dysbacteriosis-induced disease; however, the role of intestinal bacteria in colorectal cancer is unclear. This review explores the role of intestinal flora in colorectal cancer. In total, 57 articles were included after identification and screening. The pertinent literature on floral metabolites in colorectal cancer from three metabolic perspectives – including carbohydrate, lipid, and amino acid metabolism – was analyzed. An association network regarding the role of intestinal flora from a metabolic perspective was constructed by analyzing the previous literature to provide direction and insight for further research on intestinal flora in colorectal cancer. Keywords: colorectal cancer, bacteria, microbiology, carbohydrate metabolism, lipid metabolism, amino acids, inflammationhttps://www.dovepress.com/role-of-intestinal-flora-in-colorectal-cancer-from-the-metabolite-pers-peer-reviewed-article-CMARFloraBacteriaColorectal cancerMetabolites |
| spellingShingle | Han S Gao J Zhou Q Liu S Wen C Yang X Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review Cancer Management and Research Flora Bacteria Colorectal cancer Metabolites |
| title | Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review |
| title_full | Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review |
| title_fullStr | Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review |
| title_full_unstemmed | Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review |
| title_short | Role of intestinal flora in colorectal cancer from the metabolite perspective: a systematic review |
| title_sort | role of intestinal flora in colorectal cancer from the metabolite perspective a systematic review |
| topic | Flora Bacteria Colorectal cancer Metabolites |
| url | https://www.dovepress.com/role-of-intestinal-flora-in-colorectal-cancer-from-the-metabolite-pers-peer-reviewed-article-CMAR |
| work_keys_str_mv | AT hans roleofintestinalfloraincolorectalcancerfromthemetaboliteperspectiveasystematicreview AT gaoj roleofintestinalfloraincolorectalcancerfromthemetaboliteperspectiveasystematicreview AT zhouq roleofintestinalfloraincolorectalcancerfromthemetaboliteperspectiveasystematicreview AT lius roleofintestinalfloraincolorectalcancerfromthemetaboliteperspectiveasystematicreview AT wenc roleofintestinalfloraincolorectalcancerfromthemetaboliteperspectiveasystematicreview AT yangx roleofintestinalfloraincolorectalcancerfromthemetaboliteperspectiveasystematicreview |