Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold
The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities. Several modifications in the thiadiazole ring have been made, proving it to be more potent and highly effective with a less toxic scaffold...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Chemistry |
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| Online Access: | https://www.mdpi.com/2624-8549/4/4/107 |
| _version_ | 1797460856739463168 |
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| author | Tulika Anthwal Sarvesh Paliwal Sumitra Nain |
| author_facet | Tulika Anthwal Sarvesh Paliwal Sumitra Nain |
| author_sort | Tulika Anthwal |
| collection | DOAJ |
| description | The chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities. Several modifications in the thiadiazole ring have been made, proving it to be more potent and highly effective with a less toxic scaffold for various biological activities. There are several marketed drugs containing 1,3,4-thiadiazole ring in their structure. In this review article, we have tried to compile the newly synthesized 1,3,4-thiadiazole derivatives possessing important pharmaceutical significance since 2014. |
| first_indexed | 2024-03-09T17:12:04Z |
| format | Article |
| id | doaj.art-1fe90cd25d2f49daa0344d3de13ef480 |
| institution | Directory Open Access Journal |
| issn | 2624-8549 |
| language | English |
| last_indexed | 2024-03-09T17:12:04Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemistry |
| spelling | doaj.art-1fe90cd25d2f49daa0344d3de13ef4802023-11-24T13:58:48ZengMDPI AGChemistry2624-85492022-12-01441654167110.3390/chemistry4040107Diverse Biological Activities of 1,3,4-Thiadiazole ScaffoldTulika Anthwal0Sarvesh Paliwal1Sumitra Nain2Department of Pharmacy, Banasthali Vidyapith, Tonk 304022, Rajasthan, IndiaDepartment of Pharmacy, Banasthali Vidyapith, Tonk 304022, Rajasthan, IndiaDepartment of Pharmacy, Banasthali Vidyapith, Tonk 304022, Rajasthan, IndiaThe chemistry of 1,3,4-thiadiazole is one of the most interesting scaffolds for synthesizing new drug molecules due to their numerous pharmacological activities. Several modifications in the thiadiazole ring have been made, proving it to be more potent and highly effective with a less toxic scaffold for various biological activities. There are several marketed drugs containing 1,3,4-thiadiazole ring in their structure. In this review article, we have tried to compile the newly synthesized 1,3,4-thiadiazole derivatives possessing important pharmaceutical significance since 2014.https://www.mdpi.com/2624-8549/4/4/1071,3,4-thiadiazolescaffoldspharmacological activitiesmarketed drugssynthesized derivatives |
| spellingShingle | Tulika Anthwal Sarvesh Paliwal Sumitra Nain Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold Chemistry 1,3,4-thiadiazole scaffolds pharmacological activities marketed drugs synthesized derivatives |
| title | Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold |
| title_full | Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold |
| title_fullStr | Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold |
| title_full_unstemmed | Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold |
| title_short | Diverse Biological Activities of 1,3,4-Thiadiazole Scaffold |
| title_sort | diverse biological activities of 1 3 4 thiadiazole scaffold |
| topic | 1,3,4-thiadiazole scaffolds pharmacological activities marketed drugs synthesized derivatives |
| url | https://www.mdpi.com/2624-8549/4/4/107 |
| work_keys_str_mv | AT tulikaanthwal diversebiologicalactivitiesof134thiadiazolescaffold AT sarveshpaliwal diversebiologicalactivitiesof134thiadiazolescaffold AT sumitranain diversebiologicalactivitiesof134thiadiazolescaffold |