Differential modulation of human GABAC-ρ1 receptor by sulfur-containing compounds structurally related to taurine

Differential modulation of human GABAC-ρ1 receptor by sulfur-containing compounds structurally related to taurine

Abstract Background The amino acid taurine (2-Aminoethanesulfonic acid) modulates inhibitory neurotransmitter receptors. This study aimed to determine if the dual action of taurine on GABAC-ρ1R relates to its structure. To address this, we tested the ability of the structurally related compounds hom...

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Bibliographic Details
Main Authors: Lenin David Ochoa-de la Paz, Martin González-Andrade, Herminia Pasantes-Morales, Rodrigo Franco, Rubén Zamora-Alvarado, Edgar Zenteno, Hugo Quiroz-Mercado, Roberto Gonzales-Salinas, Rosario Gulias-Cañizo
Format: Article
Language:English
Published: BMC 2018-08-01
Series:BMC Neuroscience
Subjects:
Receptor modulation
GABA receptor
Xenopus oocytes
Sulfur-containing compounds
Taurine
Homotaurine
Online Access:http://link.springer.com/article/10.1186/s12868-018-0448-6

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