Clinical Evaluation of Metagenomic Next-Generation Sequencing Method for the Diagnosis of Suspected Ascitic Infection in Patients with Liver Cirrhosis in a Clinical Laboratory

Clinical Evaluation of Metagenomic Next-Generation Sequencing Method for the Diagnosis of Suspected Ascitic Infection in Patients with Liver Cirrhosis in a Clinical Laboratory

ABSTRACT Metagenomic next-generation sequencing (mNGS), mostly carried out in independent clinical laboratories, has been increasingly applied in clinical pathogen diagnosis. We aimed to explore the feasibility of mNGS in clinical laboratories and analyze its potential in the diagnosis of infectious...

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Bibliographic Details
Main Authors: Hao-Xin Wu, Fei-Li Wei, Wei Zhang, Jie Han, Shan Guo, Zheng Wang, De-Xi Chen, Wei Hou, Zhong-Jie Hu
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:Microbiology Spectrum
Subjects:
metagenomic next-generation sequencing
ascitic infection
diagnosis
clinical laboratories
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02946-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02946-22

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